Article type
Year
Abstract
Objectives: To critically assess the possible effect of Integrative traditional Chinese and western medicine in the treatment of SARS.
Methods: Identified randomized controlled trials of Chinese herbs combine with western medicine in the treatment of SARS by systematically literature searching without any limitations on language or publication status. Additional studies of gray literature were also collected. All the data were collected before September 2004.The quality of studies was evaluated by two investigators independently based largely on the quality criteria specified CONSORT and Cochrane Reviewers Handbook recommended. The statistical analysis of results was performed by using of RevMan 4.2.3.
Results: Six studies (n=366) fulfilling the inclusion criteria were found. Of six studies, the quality of one study was graded as B, the other five were graded as C. Two studies were performed meta-analysis; the other four studies exist some heterogeneity. In the treatment groups of these two studies, they showed a significant effect on lung infiltrate absorption (OR 6.68, 95% CI, 2.93~15.24, Z=4.52); no significant differences were showed on the effects of mortality and other symptom improvement including loss of dyspnea and cough.
Conclusion: It have showed that integrative traditional Chinese and western medicine was some positive effects on SARS patients in lung infiltrate absorption. Further careful study on potential usefulness of integrative traditional Chinese and western medicine for SARS as an adjunct treatment is recommended.
Methods: Identified randomized controlled trials of Chinese herbs combine with western medicine in the treatment of SARS by systematically literature searching without any limitations on language or publication status. Additional studies of gray literature were also collected. All the data were collected before September 2004.The quality of studies was evaluated by two investigators independently based largely on the quality criteria specified CONSORT and Cochrane Reviewers Handbook recommended. The statistical analysis of results was performed by using of RevMan 4.2.3.
Results: Six studies (n=366) fulfilling the inclusion criteria were found. Of six studies, the quality of one study was graded as B, the other five were graded as C. Two studies were performed meta-analysis; the other four studies exist some heterogeneity. In the treatment groups of these two studies, they showed a significant effect on lung infiltrate absorption (OR 6.68, 95% CI, 2.93~15.24, Z=4.52); no significant differences were showed on the effects of mortality and other symptom improvement including loss of dyspnea and cough.
Conclusion: It have showed that integrative traditional Chinese and western medicine was some positive effects on SARS patients in lung infiltrate absorption. Further careful study on potential usefulness of integrative traditional Chinese and western medicine for SARS as an adjunct treatment is recommended.