Assessing risk of bias in included studies: the recommended tool for Cochrane reviews

Article type
Authors
Higgins J, Gagnier J
Abstract
Objective:
To provide initial training to review authors in the recommended tool for assessing risk of bias in Cochrane reviews.
Description:
Assessment of the (internal) validity of included studies is an important part of a Cochrane review. A new tool was implemented in RevMan 5, and is described in detail in version 5 of the Cochrane Handbook for Systematic Reviews of Interventions. The 'Risk of bias' table is an extension of the table of 'Characteristics of included studies'.
The tool involves providing a description of what happened in the study, and a judgement of whether this was sufficient to avoid a high risk of bias, for each in a series of key domains. The default domains for assessment of a clinical trial are sequence generation, allocation sequence concealment, blinding, incomplete outcome data, selective reporting and 'other' risks if bias.
The workshop will introduce the new tool and offer the opportunity for participants to try it out on a report of a clinical trial. Participants are welcome to bring their own trial report.