Background: The Cochrane Gynaecological Cancer Review Group (CGCRG) has been awarded an NHS Cochrane Collaboration Programme Grant which will help support authors preparing systematic reviews on topics of high priority to NHS patients. When the major gynaecological cancer sites are combined, they have the second highest incidence of any female cancer in the UK (17,413 cases in 2003, UKCR figures) behind breast cancer and ahead of colorectal and lung cancer. Mortality from gynaecological cancer in the UK (7661 deaths in 2004, UKCR figures) is only lower than lung and breast cancer. The NHS has made major improvements in gynaecological cancer care, and it is one of the most integrated and multidisciplinary areas in medicine with an active Improving Outcome Guidance programme. This is important as there are seven tumour sites with multiple complex care pathways. The CGCRG is a highly collaborative multidisciplinary group with a good track record in developing teams to prepare reviews. The most active UK members of the group form the core of this award scheme and have strong links to all the major national professional and consumer organisations involved in gynaecological cancer. Objectives: The objective is to improve patient care by preparing systematic reviews, which will inform national guidelines and local protocols. Methods: The programme has identified and allocated titles to UK sub-speciality trainees in all aspects of gynaecological cancer care who expressed an interest in conducting a systematic review. Support is ongoing regarding the preparation and publication of such a review. These reviewers are attached to one of the clinical applicants and have prepared a timetable for review completion. All reviewers are receiving mentoring from their experienced clinical reviewer and methodological experts, whom they are encouraged to visit to progress the review. The editorial base is providing comprehensive support, maintaining communication between the Group’s editors and the reviewers, managing the process of statistical, methodological and external peer review. Reviews produced in this programme will be translated by BGCS and Network site specialist groups into guidelines and protocols. These protocols will be audited for compliance, by Networks and Trusts, in order to improve care.