Online information portal for evidence-based research on anxiety and trauma-related disorders

Article type
Authors
Ipser J, Stein D, Hoppe L
Abstract
Background: The Internet has fast become one of the major sources of information on anxiety disorders. In order to protect against the effects of the generally low-quality information of uncertain providence that is available, we decided to develop a website providing access to evidence based information on the identification and treatment of anxiety disorders. Objectives: This site aims to provide a portal to high-quality information on anxiety and trauma-related disorders, and to provide a platform for further investigation of these disorders. This website forms part of the Cross-University Brain and Behaviour Initiative (http://www.psychiatry.uct.ac.za/cubbi/). Methods: The site was developed using the Smarty PHP template engine. The R statistical package forms the computational backend of the system, with data from randomised controlled trials (RCTs) of treatment interventions stored in a MySQL database. Results: The site currently consists of three sections. A section on the diagnosis and assessment of anxiety disorders contains their DSM-IV-TR diagnostic criteria, and a table of measurement scales used for screening and outcome assessment. A section on treatment consists of (a) treatment algorithms for each of the anxiety disorders, (b) Cochrane reviews conducted on behalf of the MRC Anxiety and Stress Disorders Research Unit on the pharmacotherapy and psychotherapy of anxiety disorders, (c) cumulative meta-analyses of symptom severity reduction from RCTs for these conditions, and (d) a list of meta-analyses of anxiety disorder treatments published in peer-reviewed journals. Finally, a section on online resources contains a table of anxiety disorder websites, with accompanying quality and importance ratings. An additional table of online search engines for the retrieval of published, unpublished and ongoing clinical trials is also provided in this section to assist those who wish to conduct their own investigations. Conclusions: Every effort has been made to ensure that information presented on this website is based on research subscribing to the principles of evidence-based medicine. Additions to the website will be discussed at the conference, and include sections on the neuropsychology, imaging and genetics of anxiety disorders, with an initial emphasis on PTSD.