Systematic reviews of diagnostic accuracy studies. 2: assessment of methodological quality

Article type
Authors
Whiting P, Rutjes A, Leeflang M, Vlassov V, Reitsma H
Abstract
Abstract: The Cochrane Collaboration has decided to include systematic reviews of diagnostic accuracy studies in their databases. The "Cochrane diagnostic reviews methodology working group" (CDR) have developed a handbook and software to guide the process of conducting diagnostic reviews. The CDR group has developed a series of workshops, all addressing CDR group guidelines as formulated in the handbook. This workshop aims to provide an introduction to the methodology of quality assessment of diagnostic accuracy studies. The workshop will include an introduction to the five dimensions of quality assessment:
a) concepts of quality
b) empirical evidence of bias
c) how to assess quality
d) how to incorporate quality into systematic reviews
e) limitations of measuring and incorporating quality.
Statistical methods to deal with design related sources of bias and variation are discussed in a separate workshop. The workshop will include interactive exercises involving the assessment and discussion of some design characteristics by reviewing published articles.