Background: The Nigerian Branch of the South African Cochrane Centre (SACC) is engaged in an initiative to involve local consumers and has already organized a successful consumer workshop at the Nigeria Contributors meeting in February 2008 (funded through the Cochrane Discretionary Funding). In 2009, the Branch received support through the Cochrane Opportunities Fund to enhance consumer participation and involvement in dissemination of relevant Cochrane information. Objective: To describe the processes adopted to engage workshop participants to develop innovative culturally-based strategies (drama, storytelling and community campaign/advocacy) for communicating Cochrane evidence on malaria and HIV/AIDS prevention and control in Nigeria. Methods: We conducted two workshops in each of the four regions in Nigeria (south west, north central, east central, and south-south); the first being a two day workshop (phase 1) and the second a follow-up one day workshop (phase 2). The first two-day workshop was organized to: (1) introduce consumers to Cochrane s high-quality healthcare information on malaria and HIV/AIDS, and (2) to support them to develop tools for dissemination. A second one-day workshop was held three months later to further develop dissemination materials and support consolidation. Results: Overall, representatives of 67 community-based, nongovernmental, and civil society organizations in each of the four workshop locations used the information shared from Cochrane Reviews to develop culturally-based strategies for communicating Cochrane evidence on malaria and HIV/AIDS prevention and control. Details of each of the group s strategies will be presented at the Colloquium. Conclusions: Activity-oriented workshops for consumers/community organizations can be a useful way of developing culturally appropriate tools for communicating Cochrane evidence on malaria and HIV/AIDS prevention and control in developing countries.