Background: In November 1997, the Chinese Evidence-Based Medicine Center (CEBMC) was established and in 1999, the Chinese Cochrane Center was successfully registered with the Cochrane Collaboration. Since then the concept of evidence-based decisionmaking became more and more popular for not only clinicians but also policy makers. Objective: To describe the current status and development of evidence-based decision-making in China. Methods: We searched three main medical databases CNKI (China National Knowledge Infrastructure/Chinese Academic Journals full text Database), VIP (a full text database of China) and CBM disc (China Biomedicine Database Disc) using the term from 1991~2010. The search terms were evidence based , evidence-based medicine , evidence-based decision-making , and so on. Results: There were more than 30 000 papers discussed with evidence-based theory and practice in Chinese academic journals, five Evidence-Based Medical Journals and more than 50 evidence based books published from 1996 to 2010. More than 10 Virtual Research Center of EBM (Ministry of Education) were established and five Asian-Pacific conferences on Evidence-Based Medicine were held. Conclusions: The concept of evidence-based decision-making has been widely accepted in China. More and more government officials, researchers and consumers become interested in evidence-based principles. Evidence-based Decision-Making is under rapid development in China.