Article type
Year
Abstract
Background: Policymakers need high-quality evidence to make appropriate decisions. United States (US) and international agencies have sought help from the Cochrane HIV/AIDS Review Group (CRG) in developing such evidence for guidelines and other policy statements.
Objectives: To ensure that HIV/AIDS policy and guidelines are based on the best evidence.
Methods: We review our experience with providing systematic reviews for state, national and international agencies and how they have been used.
Results: Between 2001 and 2011 our group has been commissioned to conduct 42 systematic reviews for state, national and international agencies, including the US Centers for Disease Control and Prevention (7), the World Health Organization (31), the California Department of Health Services (3) and the US Council on Foreign Relations (1). Since 2008, we have conducted 22 reviews (including more than 70 GRADE profiles) for the World Health Organization. These evidence assessments have been used to develop worldwide guidelines for antiretroviral therapy of adults, adolescents and children, prevention of mother-to-child transmission, prevention of sexual transmission among men who have sex with men, prevention of sexual transmission among couples, and prevention, diagnosis and treatment of cryptococcal infection.
Conclusions: For a decade, evidence generated by our CRG has helped guide regional, national and global HIV/AIDS guidelines.
Objectives: To ensure that HIV/AIDS policy and guidelines are based on the best evidence.
Methods: We review our experience with providing systematic reviews for state, national and international agencies and how they have been used.
Results: Between 2001 and 2011 our group has been commissioned to conduct 42 systematic reviews for state, national and international agencies, including the US Centers for Disease Control and Prevention (7), the World Health Organization (31), the California Department of Health Services (3) and the US Council on Foreign Relations (1). Since 2008, we have conducted 22 reviews (including more than 70 GRADE profiles) for the World Health Organization. These evidence assessments have been used to develop worldwide guidelines for antiretroviral therapy of adults, adolescents and children, prevention of mother-to-child transmission, prevention of sexual transmission among men who have sex with men, prevention of sexual transmission among couples, and prevention, diagnosis and treatment of cryptococcal infection.
Conclusions: For a decade, evidence generated by our CRG has helped guide regional, national and global HIV/AIDS guidelines.