Article type
Year
Abstract
Objectives: To evaluate the efficacy of integrated traditional Chinese and Western medicine in treating of early post-operative inflammatory ileus (EPII).
Methods: We searched CBM (1978–2010.6), CNKI (1979–2010.6), VIP(1989–2010.6), Wanfang (1998–2010.6), PubMed (1996–2010.3). No language restrictions were applied. Randomized controlled trials (RCTs) of patients with EPII were included. The quality of included studies were evaluated and meta-analysis was performed by RevMan 4.2.10 software.
Results: Twenty-one RCTs, encompassing a total of 1901 patients, were included. The meta-analysis showed that: (1) For integrated traditional and western medicine versus western medicine alone: Cure rate: Eleven studies showed that integrated traditional and westernmedicine treatment group were higher than western medicine treatment group in cure rate. There were significant differences between the two groups [OR=4.54, 95% CI (2.91, 7.06), P<0 .00001]; Total effective rate: Five studies showed that integrated traditional and western medicine treatment group were higher than western medicine treatment group in total effective rate rate. There were significant differences between the two groups [OR = 10.53, 95% CI (4.27, 25.97), P < 0.00001]. ⊗The time of gas passage: Four studies showed that integrated traditional and westernmedicine treatment groupwere less than westernmedicine treatment group in the time of gas passage. There were significant differences between the two groups [SMD= −2.32, 95% CI (−3.91, −0.74) P=0.004]; The average stay in hospital: six studies showed that integrated traditional and western medicine treatment group were less than western medicine treatment group in the average stay in hospital. There were significant differences between the two groups [WMD = −5.59, 95% CI (−9.20, −1.98), P = 0.002]; (2) Between the two groups of integrated traditional and western medicine: Two studies showed that treatment group were higher than control group in cure rate. There were significant differences between the two groups [OR = 2.92, 95% CI (1.31, 6.51), P = 0.009]; (3) Traditional Chinese Medicine alone western medicine alone: Cure rate: Two studies showed that traditional Chinese Medicine treatment group were higher than western medicine treatment group in cure rate. There were significant differences between the two groups [OR = 5.01, 95% CI (2.07, 12.17), P=0.0004]; Total effective rate: Two studies showed that traditional Chinese Medicine treatment group were higher than western medicine treatment group in total effective rate rate. There were significant differences between the two groups [OR = 10.18, 95% CI (4.45, 23.26), P < 0.00001].
Conclusions: Compared with the western medicine, integrated traditional and western medicine in the treatment of EPII patients can effectively improve cure rate and total effective rate, and shorten the time of gas passage and average stay in hospital.
Methods: We searched CBM (1978–2010.6), CNKI (1979–2010.6), VIP(1989–2010.6), Wanfang (1998–2010.6), PubMed (1996–2010.3). No language restrictions were applied. Randomized controlled trials (RCTs) of patients with EPII were included. The quality of included studies were evaluated and meta-analysis was performed by RevMan 4.2.10 software.
Results: Twenty-one RCTs, encompassing a total of 1901 patients, were included. The meta-analysis showed that: (1) For integrated traditional and western medicine versus western medicine alone: Cure rate: Eleven studies showed that integrated traditional and westernmedicine treatment group were higher than western medicine treatment group in cure rate. There were significant differences between the two groups [OR=4.54, 95% CI (2.91, 7.06), P<0 .00001]; Total effective rate: Five studies showed that integrated traditional and western medicine treatment group were higher than western medicine treatment group in total effective rate rate. There were significant differences between the two groups [OR = 10.53, 95% CI (4.27, 25.97), P < 0.00001]. ⊗The time of gas passage: Four studies showed that integrated traditional and westernmedicine treatment groupwere less than westernmedicine treatment group in the time of gas passage. There were significant differences between the two groups [SMD= −2.32, 95% CI (−3.91, −0.74) P=0.004]; The average stay in hospital: six studies showed that integrated traditional and western medicine treatment group were less than western medicine treatment group in the average stay in hospital. There were significant differences between the two groups [WMD = −5.59, 95% CI (−9.20, −1.98), P = 0.002]; (2) Between the two groups of integrated traditional and western medicine: Two studies showed that treatment group were higher than control group in cure rate. There were significant differences between the two groups [OR = 2.92, 95% CI (1.31, 6.51), P = 0.009]; (3) Traditional Chinese Medicine alone western medicine alone: Cure rate: Two studies showed that traditional Chinese Medicine treatment group were higher than western medicine treatment group in cure rate. There were significant differences between the two groups [OR = 5.01, 95% CI (2.07, 12.17), P=0.0004]; Total effective rate: Two studies showed that traditional Chinese Medicine treatment group were higher than western medicine treatment group in total effective rate rate. There were significant differences between the two groups [OR = 10.18, 95% CI (4.45, 23.26), P < 0.00001].
Conclusions: Compared with the western medicine, integrated traditional and western medicine in the treatment of EPII patients can effectively improve cure rate and total effective rate, and shorten the time of gas passage and average stay in hospital.