Advancing quality in health policy decision-making in the face of uncertainty: an integrated review to characterize and address uncertainty

Article type
Authors
Brouwers M1, Driedger M2, Makarski J1, Craigie S1, Annable G2
1Department of Oncology, McMaster University, Canada
2Department of Community Health Sciences, University of Manitoba, Canada
Abstract
Background: Evidence-based decision-making has become a cornerstone of effective health care in both clinical and policy contexts. Specific to the health policy setting, decision-makers must make decisions within the context of uncertainty, a phenomenon that has been poorly understood. Specifically, while research in this area has focused on key themes, a better articulation of the specific types of uncertainty, their impacts, and strategies available to navigate or mitigate them are warranted.

Objectives: Our aim was to identify and characterize the unique uncertainties experienced by health policy decision-makers and to identify strategies for how to deal with them. A systematic review of the literature was undertaken to identify: (1) types and sources of uncertainty that decision-makers experience; (2) the impacts of these sources of uncertainty on decision-making; and (3) strategies to measure, navigate, and mitigate uncertainty.

Methods: Scopus and Ovid Medline databases (1995–2011) were searched for English language articles relating to health policy and uncertainty, complemented by a targeted book review and search of the grey literature.

Results: A total of 292 articles met inclusion. Three domains comprising 12 factors were identified: scientific (clinical, methods, evidence, statistics, models, generalizability), structural (adoption, practical, affordability), and contextual (acceptance, political, values). Impacts of uncertainty included delayed action, avoidance, suboptimal decisions and non-recommendation. Over 30 formal strategies to deal with uncertainty were identified, ranging from statistical methodologies, to formal methods used in policy contexts, to broader principles (e.g., Precautionary Principle).

Conclusions: We successfully characterized uncertainty in the health policy context and created a working framework. These findings will be taken forward to develop a tool to assist health policy decision-makers to navigate uncertainty.