How to addressing equity in guidelines: a review

Article type
Authors
Shi CH1, Zhang L2, Wang Q1, Tian JH1, Guo Y3, Yang KH1
1Evidence Based Medicine Centre of Lanzhou University, China
2Evidence Based Medicine Centre of Lanzhou University, China; School of Basic Medical Sciences, Lanzhou University, China
3Evidence Based Medicine Centre of Lanzhou University, China; The Second School of Clinical Medicine, Lanzhou University, China
Abstract
Background: Over the past decade, clinical practice guidelines (CPGs) have increased to assist practitioner and patient decisions for specific clinical circumstances. And they also have focused on the effectiveness and cost-effectiveness of interventions to balance benefits versus harms and cost. However, equity rarely is addressed in CPGs.

Objectives: To review methodologies on how to incorporate equity into CPGs.

Methods: We electronically searched MEDLINE, retrieved references and browsed guidelines development organizations’ websites to identify eligible studies that described when, how and to what extent equity should be incorporated into CPGs. Then, general characteristics and checklists/frameworks from included studies were investigated. Ignoring the irrelevant content of studies, we only retrieved all questions/items on equity issues from checklists/frameworks and grouped them into different themes. Finally, according to these checklists/frameworks, content analysis was independently conducted to decide whether they covered the most themes.

Results: Finally, 10 studies (17 checklists/frameworks) were included. Then 87 questions/items were collected from them and grouped into 6 themes (scope, search, appraisal, formulate recommendations, monitor implementation, assess the quality of CPGs). With content analysis, only ‘checklists for scoping, early guideline development and formulating recommendations’ from NICE 2012 covered the most themes. But they did not recommend any grading systems or criterion on scores. Four studies (Eslava-Schmalbach J 2011, Aldrich R 2003, NHMRC 2003 and Keuken DG 2007) recommended a process to address equity issues into CPG, including identifying equity issues, searching evidence, appraising evidence and making recommendations.

Conclusion: We find that when guidelines are to be developed, NICE 2012 checklists have the most potential to be as a tool to guide how to address equity into guidelines. However, important limitations, such as a lack of the recommended search strategy and monitoring stategy of CPGs implementations need to be dealt with.