Search strategies and data sources for adverse effects reviews

Article type
Authors
Golder S1, Zorzela L2
1CRD, United Kingdom
2University of Alberta, Canada
Abstract
Objective:

To give guidance for review authors on the available data sources on adverse effects, and how to retrieve data for incorporation into a systematic review. This will include the development of optimal search techniques and discussion of the diverse formats of adverse effects data sources.

Description:

Participants will receive a number of scenarios, and will then work together in small groups to plan a search strategy for a comprehensive evaluation of adverse effects. The scenarios will be drawn from real-life situations to cover a wide range of potential adverse effects, such as: (1) There have been safety concerns arisen about the risk of fractures with thiazolidinediones. (2) Patients with epilepsy often have to take long-term medication to control their symptoms, and there are concerns over the safety and tolerability of the drugs. At the end, groups will feedback on their protocols, and any points raised will be discussed further. Examples from existing reviews will be provided by the facilitator, as well as tips and tricks to solve specific issues.