Introduction to meta-analysis 4: meta-analysis of time-to-event data

Article type
Authors
Nolan S1, Efthimiou O2, Trivella M3
1Cochrane Epilepsy Group
2Department of Hygiene and Epidemiology, University of Ioannina, School of Medicine
3Centre for Statistics in Medicine, Oxford University
Abstract
Objectives:
Time-to-event data, such as time to death or time to first seizure, are commonly used outcomes in medical research to summarise the length of time taken for a particular event of interest to occur. This workshop will discuss how to undertake a meta-analysis of time-to-event data.

Description:
Methods for analysis of time-to-event data need to account for both the time to event and any related but unobserved events. Meta-analysis of time-to-event outcomes can be undertaken using data extracted from trial reports using a variety of different methods including an alternative more resource-intensive approach which involves a re-analysis of individual participant data.