Setting research priorities with multiple professions and service users

Article type
Authors
Uhm S1, Alderdice F2, Brady I3, Chambers B4, Chivers Z5, Crowe S6, David A7, Deshpande S8, Gale C9, Gyte G10, Oliver S11, James P7, Duley L12, McNeill J2, Shennan A13, Turner M14, Oliver S11
1Institute of Education, London and Kookmin University, United Kingdom
2TinyLife, Belfast, United Kingdom
3Irish Premature Babies, Ireland
4Unknown, Unknown
5Bliss, London, United Kingdom
6James Lind Alliance, United Kingdom
7UCL Institute for Women’s Health, London, United Kingdom
8British and Irish Paediatric Pathology Association, United Kingdom
9Imperial College, London, United Kingdom
10National Childbirth Trust, United Kingdom
11EPPI-Centre, Institute of Education, United Kingdom
12Nottingham Clinical Trials Unit, University of Nottingham, United Kingdom
13Kings College London, London, United Kingdom
14Liverpool Women’s NHS Foundation Trust, Liverpool, United Kingdom
Abstract
Background:
Preterm birth is the most important determinant of adverse infant outcomes including survival, quality of life, psychosocial impact on the family, and healthcare costs. Research agendas in this area have been determined primarily by researchers.

Objectives:
To identify and prioritize future research areas in preterm birth that are most important to service users and practitioners.

Methods: A priority setting partnership was established with: organisations representing families in the British Isles with experience of preterm birth, obstetricians, neonatologists, midwives, and neonatal nurses. Research uncertainties were gathered from surveys of service users and healthcare practitioners, and analyses of systematic reviews and clinical guidance. Priorities were set through on-line voting and paper surveys, and further distilled in a facilitated workshop, as advocated by the James Lind Alliance.

Results: Eliciting research suggestions from all types of stakeholders required extensive networking. 593 uncertainties were submitted by 386 respondents (58% service users, 30% healthcare professionals and 12% from those in both roles); 52 were identified from literature reviews. After merging similar questions, 104 were distributed for voting. The 30 most popular items were discussed at a workshop with service users and professionals, and the top 15 questions put in priority order. These include prevention and prediction of preterm birth, neonatal infection, lung damage, necrotising enterocolitis, pre-eclampsia, preterm premature rupture of the membranes, optimal neonatal feeding strategy, pain perception and management, a care package at neonatal discharge, emotional and practical support, attachment and bonding, and the best time for cord clamping.

Conclusions: 15 top priorities provide guidance for researchers and funding bodies to ensure that future research addresses questions that are important to service users and clinicians. Challenges for the priority setting partnership included maximizing participation amongst people most affected by preterm birth; the breadth of the topic; and securing input from an appropriate range of clinicians.