Use of information from summary of findings tables in the clinical practice guidelines development: a pilot study in Colombia

Article type
Authors
Rojas MX1, Rodriguez A1, Gómez C1, Santesso N2
1Pontificia Universidad Javeriana, Colombia
2McMaster University, Canada
Abstract
Background:
The goal of the inclusion of GRADE (Grading of Recommendations Assessment, Development and Evaluation) summary of findings (SoF) tables in Cochrane Reviews (CRs) is to provide a concise and transparent summary of the key findings of the review. The SoF tables in CRs differ from GRADE evidence profiles (GP) in their detail and quality; while the GP present it in detail, the SoF table only provides the key information needed for decision-making. How useful the guideline developing groups (GDG) find the SoF tables as they are currently presented in the CRs remains uncertain. This study aimed to describe the experience of using the SoF tables from CRs by the Colombian GDGs that have adopted the use of GRADE as part of the guideline development.

Objectives:
To assess the understanding of SoF tables and GP information by GDGs. To describe the use that GDGs are doing with SoF tables and GP information in the formulation of recommendations. To identify: 1) how much technical teams and GDGs use the SoF tables of Cochrane reviews in the preparation of information for panel members; 2) the reasons for not using SoF tables of CRs or for developing new GRADE profiles based in the same CRs.

Methods:
We conducted a semi-structured interview with individuals and groups that have applied the GRADE approach in the context of guidelines development. From the national register of GDGs, we identified and invited the eligible participants to take part in the study. Personal interviews were conducted relating to specific CRs or guidelines to assess the understanding the SoF tables and the application of GP results in the formulation of their recommendations. All interviews responses were recorded and written interview summaries were validated with the participants.

Results:
As part of a pilot study we have performed 12 interviews to technical team members and 8 to members of GDG. The responses obtained from implementing the above mentioned methods will be presented.

Conclusions:
Results provide useful information for developing future larger survey in GDGs from other organizations and generating actions for improving the CRs.