Objectives: Cochrane Reviews often include findings from cross-cultural studies in which data from questionnaires completed by both clinicians and patients are pooled. This workshop aims to acquaint participants with ways to evaluate and grade the methods used to translate and adapt patient- and clinician-reported outcome (PROs and ClinROs) measures used in clinical trials across language and cultural groups.
Description: Three 30 minute sessions will include:
1. a presentation of the concept of cultural adaptation based on linguistic validation, followed by a group exercise evaluating an item in cultural adaptation;
2. examination of selected Cochrane Reviews and discussion of how the methods of translation are reported and can be reviewed (if at all); and
3. discussion of the effects of variability in cross-cultural questionnaire data on pooling, including implications for trial sample size. An example of data pooling will be presented and discussed.