Article type
Year
Abstract
Biomedical research should lead to improvements in healthcare to provide value for research investment and reduce waste of resources. Selecting research through agreement with those that develop and use it is key to increasing this value.
GENERATE is an initiative in ENT (Ear, Nose & Throat) Hearing and Balance to raise awareness of the need for high value research in this field, and to develop an agenda and the collaborations needed to deliver the agenda.
Based on a narrative review of research priority-setting exercises, GENERATE used a multi-stage process to develop a consensus-based research agenda overseen by an independent steering committee. Stakeholders were identified through an iterative process. Research topics were identified through a survey and focus groups. To avoid individual bias responses and transcripts were analysed by two independent researchers by framework analysis, with three senior researchers analysing independent samples of the data. The framework was inductively developed from the data by open coding to identify themes. The data were coded into the framework and topics that appeared across multiple themes and with the greatest weight of response will be discussed in an Expert Forum to identify areas lacking in research. Prioritisation to develop the final agenda will occur in a facilitated multi-stakeholder consensus conference.
The survey had 685 responses: 326 were from patients/members of the public: healthcare professionals from 27 different disciplines responded; five focus groups were held with patients, clinicians, researchers, service managers and commissioners and industry representatives; we identified seven themes, with individual subthemes (fig 1) from the data.
GENERATE promoted broad engagement from multiple stakeholders to develop a research agenda. Rigorous analysis of responses resulted in the agenda moving away from traditional biomedical themes of most agendas, reflecting the diversity of response while still capturing the clarity of the questions raised.This framework promotes the collaboration needed for value-based, implementable research by dispensing with the traditional 'silos' for research.
GENERATE is an initiative in ENT (Ear, Nose & Throat) Hearing and Balance to raise awareness of the need for high value research in this field, and to develop an agenda and the collaborations needed to deliver the agenda.
Based on a narrative review of research priority-setting exercises, GENERATE used a multi-stage process to develop a consensus-based research agenda overseen by an independent steering committee. Stakeholders were identified through an iterative process. Research topics were identified through a survey and focus groups. To avoid individual bias responses and transcripts were analysed by two independent researchers by framework analysis, with three senior researchers analysing independent samples of the data. The framework was inductively developed from the data by open coding to identify themes. The data were coded into the framework and topics that appeared across multiple themes and with the greatest weight of response will be discussed in an Expert Forum to identify areas lacking in research. Prioritisation to develop the final agenda will occur in a facilitated multi-stakeholder consensus conference.
The survey had 685 responses: 326 were from patients/members of the public: healthcare professionals from 27 different disciplines responded; five focus groups were held with patients, clinicians, researchers, service managers and commissioners and industry representatives; we identified seven themes, with individual subthemes (fig 1) from the data.
GENERATE promoted broad engagement from multiple stakeholders to develop a research agenda. Rigorous analysis of responses resulted in the agenda moving away from traditional biomedical themes of most agendas, reflecting the diversity of response while still capturing the clarity of the questions raised.This framework promotes the collaboration needed for value-based, implementable research by dispensing with the traditional 'silos' for research.