Cochrane Reviews to support clinical guidelines: the opportunities and challenges of collaborating with guideline developers

Article type
Year
Authors
Kellie F1, West H1, Alfirevic Z1, Neilson J1, Hampson L1, Dowswell T1, Jones L1
1Cochrane Pregnancy and Childbirth, University of Liverpool, UK
Abstract
Objectives: Bridging the gap between research and healthcare policy is challenging. As part of our NIHR (National Institute for Health Research) Cochrane programme grant we will produce Cochrane Reviews tailored to the needs of UK clinical guideline developers.

Methods: A total of 45 new or updated Cochrane Reviews will be produced as part of this three-year project. Topics have been identified by the Royal College of Obstetrics and Gynaecology (RCOG) and the National Collaborating Centre for Women's and Children's Health (NCC-WCH) who develop guidelines for NICE (National Institute for Health and Care Excellence), to dovetail into planned guideline development in four areas where evidence continues to accrue.
- Management of breech presentation
- Multiple pregnancy
- Induction of labour
- Diabetes in pregnancy

Opportunities and challenges:
- All reviews to include a section on implications for practice, confirming support for existing standards or providing a basis for new care standards.
- Updating several reviews on a topic enables us to standardise outcome measures and improve the consistency between reviews in the same topic area.
- Guidelines may focus on different PICO (population, intervention, comparison, outcomes) questions to the ones posed by Cochrane Reviews.
- Additional products including 'Summary of findings' tables, GRADE (Grading of Recommendations, Assessment, Development and Evaluations) evidence profiles, improved Plain language summaries, and infographics will distil the message of reviews, increase accessibility, and make them more useful to guideline developers.
- A fast-tracked peer review and editorial process will ensure rapid publication, so evidence will be up-to-date when guidelines are produced.