Improvement of the development of clinical practice guidelines: Use of systematic reviews in its construction

Article type
Authors
Barrera-Cruz A1, Millan-Gamez YK1, Viniegra-Osorio A1, Martínez-Chapa HD1
1Mexican Social Security Institute
Abstract
Background: Clinical Practice Guidelines (CPGs) are technical tools that contribute to improve the quality of healthcare, reducing it´s heterogeneity, systematising interventions and collaborating with the efficient use of resources.

Objectives:To identify the total number of systematic reviews (SRs) that are used in the construction of CPGs, as well as identifying the percentage of SRs that are Cochrane made or not.

Methods: Retrospective analysis of CPGs that will be developed in 2015 and 2016 by the Mexican Social Security Institute. The topics selected for the development and updating of the CPGs fulfill the following criteria of prioritisation: magnitude, transcendence, impact, costs, vulnerable groups, as well as strategic programs of the national health system. The CPGs were classified by specialty, attention level and type of development (new creation or update).

Results:The sample included 74 CPGs. During 2015, for the development of 40 CPGs (25 new and 15 updated) (Figure 1), 176 SRs were consulted, of which 27% (48/176) were created by Cochrane, while in 2016, for the development of 34 CPGs (14 new and 20 updated), 191 SRs were consulted, of which 29% (56/191) were developed by Cochrane (Figure 2). The medical specialties that used the highest proportion of SRs were: ophthalmology, pediatrics and neurology. In specific topics, between 20% and 40% of the clinical evidence and recommendations of CPGs were constructed with SRs (Figure 3).

Conclusions:Evidence-based CPGs aim to improve the effectiveness, efficiency and safety of clinical decisions. A key element in its development is the incorporation of high-quality evidence, particularly SRs. We recognise that not all recommendations of CPGs can be supported by SRs. However, the inclusion of this type of evidence should be promoted. In our institution there is a tendency to increase the update of CPGs with the use of evidence of high quality that favours the creation of better health decisions.