Background: The Swedish National Board of Health and Welfare works with the aim to establish good and equal healthcare in Sweden. In a decentralised healthcare system national guidelines provide steering. Further information on improvement areas from a steering perspective can, however, be achieved by combining the guidelines with indicators for assessments, target-levels and an evaluation of current performance using national patient registries.

Objectives: The aim is to establish good and equal healthcare in Sweden by increased adherence to the guideline for multiple sclerosis.

Methods: A standardised, systematic and transparent processes to develop the guideline, which includes a body of scientific evidence with prioritised recommendations, indicators with target-levels and a National assessment and evaluation was used. These processes involve patients, professionals and decision-makers in the healthcare system. Evaluation was done based on different nationwide patient registries together with directed questionnaires.

Results: A guideline for multiple sclerosis with indicators for assessment, target-levels and a nation-wide evaluation were developed and published.

Conclusions: The integrated work provides best-available knowledge on methods to use but also on current performance in a healthcare area. As such it is a very valuable tool for healthcare providers working with development and improvement of healthcare.