Two-year follow up in a breast-screening decision aid RCT: Retention of overdetection knowledge and other decision-making effects

Article type
Authors
Hersch J1, Barratt A1, Jansen J1, Jacklyn G1, Irwig L1, McGeechan K1, Houssami N1, Dhillon H2, McCaffery K1
1School of Public Health, The University of Sydney
2Central Clinical School, The University of Sydney
Abstract
Background: Supporting women to make well-informed decisions about breast-cancer screening requires effective communication about screening outcomes including overdetection or overdiagnosis (diagnosis and treatment of cancers that would never become clinically evident).
Objectives: We investigated the effects of providing information about overdetection in a decision aid for women aged around 50 considering breast screening. Immediate post-intervention results (reported previously) showed that the intervention increased knowledge and informed choice, made screening attitudes less positive and reduced intentions to screen. We now present 2-year follow-up data.
Methods: We did a community-based RCT in Australia with a random cohort of women aged 48-50 who had not undergone mammography in the past 2 years and had no personal or strong family history of breast cancer. We randomised 879 women to receive the intervention decision aid (evidence-based information on overdetection, breast cancer mortality reduction, and false positives) or a control decision aid (identical but without overdetection information). Two years later we assessed women’s knowledge, attitudes and future screening intentions, plus screening uptake.
Results: 712 women (81% of those randomised) completed 2-year follow-up. Compared with controls, more women in the intervention group retained adequate conceptual knowledge (34% vs. 20%, p