Impact of the retracted non-Cochrane Review on clinical practice guidelines

Article type
Authors
Yang K1, Zhou Q2, Chen Y1
1Evidence-based Medicine Center, Lanzhou University
2The First Clinical Medical School, Lanzhou University
Abstract
Background: clinical practice guidelines are based on systematic review of evidence, balancing the advantages and disadvantages of different interventions, and forming recommendations that provide optimal health care for patients. However, after a published systematic review has been retracted, it is not known whether it will affect the subsequent guidelines.

Objectives: to investigate the impact of retracted non-Cochrane Review (NCR) on clinical practice guidelines.

Methods: we searched the PubMed and Embase databases from their inception until 31 March 2019. We searched using the words "Retracted, Retraction, Withdrawal, Systematic Review, Meta-analysis" as keywords combined with free text. Two researchers independently screened the records and extracted data; we resolved disagreements through discussion or by consulting a third party. We used Stata statistical software 14 to process the data and to present descriptive results.

Results: the results will be presented at the meeting.

Conclusions: the conclusions will be presented at the meeting.

Patient or healthcare consumer involvement: none