The classification and management of conflicts of interest in Chinese clinical guidelines

Article type
Authors
Xun Y1, Zhou Q2, Shi Q2, Wang Z3, Yang N1, Chen Y1
1Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University; WHO Collaborating Centre for Guideline Implementation and Knowledge Translation; Chinese GRADE Center; Cochrane China Network, Lanzhou
2The First School of Clinical Medicine, Lanzhou University, Lanzhou
3Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University; Cochrane China Network; Guideline International Network Asia; Chinese GRADE Center
Abstract
Background:Conflicts of interest can affect the credibility, independence, and quality of clinical practice guidelines. Guideline developers, users, and researchers are trying to manage and reduce conflicts of interest worldwide. The evaluation results of the report quality of the Chinese guidelines show that the “Funding and Interest "report rate is only 10% -15%. The classification and management of these conflicts of interest are unclear.

Objectives:To analyze the classification and management strategies of conflicts of interest of the Chinese guideline developers, and give suggestions on how to address conflicts of interest in clinical practice guidelines in China.

Methods:All Chinese guidelines available through MEDLINE, Web of Science, Embase, China National Knowledge Infrastructure, Wanfang, China Biology Medicine disc, Medlive (http://www.medlive.cn/) since database established until the present will be included in this review. These guidelines may be from any healthcare specialty or field for any disease or disease group. All guidelines will be assessed by at least two independent reviewers and data will be extracted independently. Guideline specialty, guideline disease area, year of publication, developing body, whether reported the conflicts of interest or not, the classification and management of these conflicts of interest, etc.

Results and conclusions: This study is ongoing and results will be presented at the Evidence summit as available.

Patient or healthcare consumer involvement: None.