Background: With the evidence-informed healthcare movement spreading across the world contextualization and applicability of evidence is becoming a key area of concern.

Objectives: To evaluate the contribution of Indian RCTs in Cochrane systematic reviews.

Methods: We searched for active Cochrane systematic reviews in all 45 Cochrane Review groups (during the period between January 2019 to June 2019. Indian studies were identified from list of Included study, excluded study, ongoing study or study awaiting classification categories

Results: We retrieved 8995 Cochrane Reviews out of which 325 had at least one Indian RCT marked in included/ ongoing studies / studies awaiting classification categories. This accounts to only 4% of the data. Indian being the tropical region and its connectivity to the Infectious Health hazards alone contributes to the highest of 12% of data in the Cochrane systematic review on interventions. There are nearly 427 Indian studies contributing data to the meta-analysis. The contribution of Indian data to the global evidence is ranging from 1% to 12% in various Cochrane reviews groups.

Conclusions: There is a need for conduct of high quality RCTs in India. Global health funders need to fund more trials in India to improve generalizability of evidence.

Patient or healthcare consumer involvement: