Coronavirus disease 2019 (COVID-19): overview of systematic review

Article type
Authors
Lu S1, Luo X2, Liu X2, Liu Y2, Ren M2, Chen Y3
1School of Medicine, University of Electronic Science and Technology of China, Chengdu
2School of Public Health, Lanzhou University, Lanzhou
3Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou
Abstract
Background: In December 2019, pneumonia caused by severe acute respiratory syndrome coronavirus2 (SARS-CoV-2) broke out in Wuhan, China. WHO declared COVID-19 to have pandemic characteristics on March 11th. There is some controversy in the academic community about how to deal with COVID-19. Systematic reviews of COVID-19 have provided recommendations and evidences for clinical trials. However, the quality of these studies are uncertain.

Objectives:The aim of our study was to assess the quality of studies published as systematic reviews (SR) or meta-analyses (MA) or rapid reviews (RR) in the field of COVID-19.

Methods:We comprehensively searched electronic databases (MEDLINE, Embase, Cochrane Database of Systematic Reviews (CDSR), CKIND, Web of Science, WANFANG) for systematic reviews published on the subject of COVID-19, and two authors independently reviewed all titles and abstracts, assessed the full text of potentially eligible studies and assessed the quality of included studies, resolving any discrepancies by discussion and with help from the third review author. We scored the quality of each SR and MA using the AMSTAR 2 checklist and ROBIS tool.

Results:Currently our search retrieved 24 studies, and report the quality of eligible systematic reviews and summarize the results of those with an AMSTAR score ≥32. We will continue to monitor the publication of COVID-19 systematic reviews and rapid reviews, the results will be presented at the conference.

Conclusions:For overview of systematic review of COVID-19, we find evidence for drugs treatment and other interventions to deconstruct some controversial clinical issues. We hope to guide the generation of better systematic evaluations in the future.

Patient or healthcare consumer involvement:None.