Diagnosis and Prediction of Different Machine Learning methods for Knee Osteoarthritis: a protocol for a systematic review

Article type
Authors
Cao L1, Liang Y2, Yang K3
1School of Public Health, Evidence-Based Social Science Research Center, Lanzhou University
2Health Research Methodology I Department of Health Research Methods, Evidence and impact, McMaster University
3Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University
Abstract
Background:

Objectives:This review aims to determine the diagnosis and prediction accuracy of different machine learning methods for Knee Osteoarthritis

Methods:Two reviewers systematically searched Cochrane, PubMed, EMBASE, and Web of Science (last updated in March 2019) for eligible articles. To identify potentially missed publications, the reference lists of the final included studies were manually screened. Outcomes assessed were test characteristics such as accuracy, sensitivity, specificity, and area under the receiver operating characteristic curve (ROC). We will use the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool to assess the risk of bias and applicability. Two independent reviewers will conduct all procedures of study selection, data extraction, and methodological assessment. Any disagreements will be consulted with a third reviewer. RevMan 5.3 software and Stata V15.0 will be used to pool data and to carry out the meta-analysis if it is possible.

Results:This systematic review will provide a high quality synthesis of machine learning for diagnose of knee Osteoarthritis from various evaluation aspects including accuracy, sensitivity, specificity and AUC.

Conclusions: The findings of this systematic review will provide latest evidence of diagnosis and prediction of different machine learning for patients with knee Osteoarthritis.
Patient or healthcare consumer involvement: Not application