Background: Evidence-based medicine (EBM) knowledge is the basic skill for medical students to encounter their future as clinician especially in the rapid-learning health systems approach that developing nowadays. However, EBM learning method on college need to be evaluated to observe its efficacy and generating a better improvement.

Objectives: To measure the efficacy of EBM training program for medical students in Faculty of Medicine, Public Health, and Nursing, UGM, Indonesia.

Methods: A cross sectional sample of 188 second year medical students were recruited to complete the ACE tool at the end of the 6 weeks consecutive EBM course, while 174 medical students who have not get the EBM training recruited as control group. We evaluate four different domains of EBM knowledge with the tool: question formulation, literature search, appraising the evidence and applying the evidence.

Results: We will measure the efficacy of EBM training by compare the difference of total average ACE score statistically between the treatment and control group. The EBM training is still on going and entered the third week when this abstract is writing.

Conclusions: We hope to see a statistical different between treatment and control group to prove that the EBM training given has a good efficacy or not.

Partner involvement: The curriculum team at the college give us permission and support to our research. We will give the recommendation for the curriculum improvement based on the results. Considering the importance of the EBM training for clinical practice in the future, we hope this result can be used by the curriculum team to evaluate its efficacy and adjust the training to the most suitable method.

Keywords: evidence-based medicine, ACE tool, efficacy, curriculum evaluation, medical students