Article type
Year
Abstract
Background:
The evidence regarding the impact of egg consumption on human health is controversial. An increasing number of systematic reviews and meta-analyses have assessed the association between egg consumption and human health.
Objectives:
Combine global evidence-based evidences to explore the relationship between egg consumption and health outcomes.
Methods:
We conducted a systematic literature search to identify systematic reviews and meta-analyses that assessed the association between egg consumption and any type of health outcome. We used AMSTAR (A MeaSurement Tool to Assess systematic Reviews) to evaluate the methodological quality of the reviews, and GRADE (Grading of Recommendations Assessment, Development and Evaluation) to determine the quality of evidence. We visualized the results using a human anatomy diagram and evidence mapping.
Results:
Our search revealed 29 systematic reviews and meta-analyses. According to the AMSTAR scores, eight studies were of high quality, fifteen studies of medium quality, and four studies of low quality (Figure 1). We identified 34 primary outcomes from the included 29 reviews, covering a total of 22 different health outcomes. According to our assessment using the GRADE approach, two of the primary outcomes were based on high-quality evidence, 18 on moderate-quality evidence, and 14 on low-quality evidence. Among the 22 health outcomes, egg consumption was found protective against two diseases, and harmful for six health outcomes. No significant association was found for ten outcomes, and the results regarding four outcomes were controversial (Figure 2).
Conclusions:
The association between egg consumption and the incidence of cancer, diabetes, cardiovascular diseases and other related diseases has been studied in several meta-analyses. The results were often controversial between studies on the same topic, which can be confusing for making dietary choices.
Patient or healthcare consumer involvement:
None.
The evidence regarding the impact of egg consumption on human health is controversial. An increasing number of systematic reviews and meta-analyses have assessed the association between egg consumption and human health.
Objectives:
Combine global evidence-based evidences to explore the relationship between egg consumption and health outcomes.
Methods:
We conducted a systematic literature search to identify systematic reviews and meta-analyses that assessed the association between egg consumption and any type of health outcome. We used AMSTAR (A MeaSurement Tool to Assess systematic Reviews) to evaluate the methodological quality of the reviews, and GRADE (Grading of Recommendations Assessment, Development and Evaluation) to determine the quality of evidence. We visualized the results using a human anatomy diagram and evidence mapping.
Results:
Our search revealed 29 systematic reviews and meta-analyses. According to the AMSTAR scores, eight studies were of high quality, fifteen studies of medium quality, and four studies of low quality (Figure 1). We identified 34 primary outcomes from the included 29 reviews, covering a total of 22 different health outcomes. According to our assessment using the GRADE approach, two of the primary outcomes were based on high-quality evidence, 18 on moderate-quality evidence, and 14 on low-quality evidence. Among the 22 health outcomes, egg consumption was found protective against two diseases, and harmful for six health outcomes. No significant association was found for ten outcomes, and the results regarding four outcomes were controversial (Figure 2).
Conclusions:
The association between egg consumption and the incidence of cancer, diabetes, cardiovascular diseases and other related diseases has been studied in several meta-analyses. The results were often controversial between studies on the same topic, which can be confusing for making dietary choices.
Patient or healthcare consumer involvement:
None.