Article type
Year
Abstract
Background: Randomized controlled trials(RCTs) are usually incorporated into systematic reviews and meta-analysis(SRs/MAs) to form the best decision evidence.In recent years, due to academic misconduct and other reasons, many RCTs have been retracted, how many retracted RCTs are included in the SR / MA, and how much impact it has on the SRs/MAs results, and how to avoid such research waste, it is worth pondering problem.
Objectives: To investigate the impact of retracted randomized controlled trials on systematic reviews and meta-analysis.
Methods: Electronic databases (including PubMed and Embase) and Retraction Watch were retrieved from their inception until March, 27 2020. We searched “Retracted, Retraction, Withdrawal, Withdrawn, Randomized Controlled Trial, placebo” words. Through citation searching of Web of Science database to find SRs/MAs that cited retracted randomized controlled trials. Finally, we will conduct sensitivity analysis for SRs/MAs to explore the impact of retracted randomized controlled trials.
Results: The results will be presented at the meeting.
Conclusions: The conclusions will be presented at the meeting.
Patient or healthcare consumer involvement: None.
Objectives: To investigate the impact of retracted randomized controlled trials on systematic reviews and meta-analysis.
Methods: Electronic databases (including PubMed and Embase) and Retraction Watch were retrieved from their inception until March, 27 2020. We searched “Retracted, Retraction, Withdrawal, Withdrawn, Randomized Controlled Trial, placebo” words. Through citation searching of Web of Science database to find SRs/MAs that cited retracted randomized controlled trials. Finally, we will conduct sensitivity analysis for SRs/MAs to explore the impact of retracted randomized controlled trials.
Results: The results will be presented at the meeting.
Conclusions: The conclusions will be presented at the meeting.
Patient or healthcare consumer involvement: None.