Research trends and Hotspots analysis of multiple sclerosis diagnosis from 2010 to 2019: a bibliometric analysis

Article type
Authors
Cao L1, Li X2, Li M1, Li Y1, Yang K1
1School of Public Health, Lanzhou University
2School of Public Health, Evidence-Based Social Science Research Center, Lanzhou University
Abstract
Background: Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system (CNS) that can cause substantial disability. It causes a major socioeconomic burden, both for the individual and for society. Like it can seriously impact on people' health-related quality of life(HR-QOL) and associated with high economic costs for patients, their families and society.

Objectives: This study aimed to comprehensively analyze the global scientific output of multiple sclerosis diagnosis research and explore the hotspots and frontiers from 2010 to 2019.

Methods: Data of publications were downloaded from the Web of Science Core Collection database We used Microsoft Excel 2016 to detect the trend of annual numbers of publications, and used Citespace V and VOSviewer 1.6.8 software as the bibliometric method to analyze the authors, journals, countries, institutions, keywords, citation reports, research hotspots, and research frontiers.

Results: Until December 30, 2019, a total of 19,042 papers in multiple sclerosis diagnosis research were identified as published between 2010 and 2019. We identified that the number of publications on multiple sclerosis diagnosis is increasing over time. The United States of America was the leading country for publications, and the leading institution was the Mayo Clinic. Co-cited reference analysis revealed the top landmark articles in the field. multiple sclerosis, diagnosis, biomarker, identification, and disease are some of the high frequency keywords in co-occurrence cluster analysis and co-cited reference cluster analysis, indicating biomarker and related diseases remain the hotspots in multiple sclerosis research.

Conclusions: This study revealed that our understanding of the link between multiple sclerosis and associated diagnosis has evolved dramatically over time. The emerging new diagnosis methods in multiple sclerosis would be the foci of future research.

Patient or healthcare consumer involvement:Not application