Background: Systematic reviews of diagnostic test accuracy summarize the accuracy of sensitivity and specificity and are important to inform evidence-based use of diagnostic tests in clinical practice. When there is a Meta-analysis, the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach is being used to assess the quality/certainty of evidence, to interpret findings, and to draw conclusions from randomised or non-randomised studies of interventions in 'Summary of findings' tables.

Objectives: To analyze how many non-Cochrane systematic reviews of diagnostic test accuracy used GRADE approach, and how the GRADE was used.

Methods: This was a methodological (research-on-research) study. We systematically retrieved non-Cochrane systematic reviews of diagnostic test accuracy from inception to March, 2020 in the following databases: MEDLINE (via PubMed), Embase, Web of Science, CBM (China Biology Medicine), CNKI (China National Knowledge Infrastructure), and Wanfang Data. Study selection and data extraction was undertaken by two reviewers independently. Extracted information about methods used for quality of evidence assessment, and if they used GRADE, we analyzed their methods and compared them with the GRADE guidelines. Descriptive statistics were used to present the data of the included studies.

Results: The results will be presented at the meeting.

Conclusions: The results will be presented at the meeting.

Patient or healthcare consumer involvement: None