What is the nature and magnitude of inappropriate healthcare services in Canada? A Systematic Review

Article type
Authors
Squires JE1, Cho-Young D1, Demery-Varin M2, Aloisio LD1, Greenough M2, Lavis J3, Bell R4, Bornstein S5, Brien S6, Décary S7, Dobrow M8, Estabrooks CA9, Graham ID1, Grinspun D10, Hillmer M11, Horsley T12, Hu J2, Katz A13, Krause C14, Légaré F15, Levinson W16, Levy A17, Mancuso M18, Maybee A19, Morgan S20, Nadalin-Penno L2, Neuner A21, Rader T22, Roberts J23, Teare G24, Tepper J25, Widmeyer D26, Wilson M27, Grimshaw J1
1Clinical Epidemiology Program, Ottawa Hospital Research Institute
2Faculty of Health Sciences, School of Nursing, University of Ottawa
3Department of Health Research Methods, Evidence, and Impact, McMaster University
4Ministry of Health and Long-Term Care
5Department of Political Science and Faculty of Medicine, Memorial University
6Public Reports, Health Quality Ontario
7Department of Family Medicine, Faculty of Medicine, Université Laval
8Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto
9Faculty of Nursing, University of Alberta
10Registered Nurses’ Association of Ontario
11Management Division, Ontario Ministry of Health and Long-Term Care
12Royal College of Physicians and Surgeons of Canada
13Manitoba Centre for Health Policy, Department of Community Health Sciences and Family Medicine, University of Manitoba
14British Columbia Patient Safety and Quality Council
15Health and Social Services Systems, Knowledge Translation and Implementation Core, Quebec SPOR Support Unit
16Institute of Health Policy, Management, and Evaluation, Department of Medicine, University of Toronto
17Department of Community Health and Epidemiology, Dalhousie University
18New Brunswick Health Council
19Patients Advisors Network
20Faculty of Medicine, School of Population and Public Health, University of British Columbia
21Health Quality Council of Alberta
22Canadian Agency for Drugs and Technologies in Health
23Patient Collaborator
24Alberta Health Services, Alberta Cancer Prevention Legacy Fund, Population, Public and Indigenous Health
25Department of Family and Community Medicine, Institute of Health Policy, Management and Evaluation
26Manitoba Institute for Patient Safety
27Department of Health Research Methods, Evidence and Impact, McMaster University
Abstract
Background: A substantial proportion of health care delivered globally is inappropriate as evidenced by harmful and/or ineffective practices being overused and effective practices being underused. This inappropriate healthcare leads to negative patient experiences, poor health outcomes, and inefficient use of scarce healthcare resources. The purpose of this study was to conduct a systematic review of inappropriate healthcare practices in Canada.

Objectives: 1) Systematically search and critically review published and grey literature on inappropriate healthcare practices in Canada. 2) Describe the nature and magnitude of inappropriate healthcare in Canada.

Methods: Multiple online databases and grey literature sources were searched to identify quantitative studies reporting objective or subjective measurements of inappropriate healthcare practices in Canada. Inclusion was limited to studies from January 2007 to September 2019 that reported on large or diverse populations. Two authors independently screened, assessed quality and extracted the data. Study findings were synthesized narratively by overuse and underuse in three care categorizations: tests, treatments, and procedures.

Results: A total of 138 studies were included. The majority of studies were conducted in the acute or specialty sector (n=74, 54%), followed by primary care (n=19, 14%). Other sectors represented less frequently included: long-term care, home and community, public health, and rehabilitation. While all Canadian regions were represented, most studies reported data from Ontario (n=85, 62%) or Alberta (n=46, 33%). Similar proportions of studies examined underuse (n=78, 56%) and overuse (n=72, 52%) of clinical practices. There was wide variation between studies in the magnitude of inappropriate care reported. Underuse of: tests ranged from 0.1% (computed tomography imaging for abdominal pain) to 100% (subjective global assessment tool for assessing malnutrition); treatments ranged 1.1% (anti-hyperglycemic medications for Diabetes) to 100% (probiotics before colorectal surgery); and procedures ranged 9.4% (endoscopy for colorectal cancer screening) to 98.1% (carotid endarterectomy/stenting for transient ischemic attack/stroke patients). Overuse of: tests ranged from 0.09% (carotid imaging) to 92.7% (breast cancer imaging); treatments ranged 0.06% (opioid use for dental pain) to 86.8% (polypharmacy (≥10 medications) among older adults); and procedures ranged 10.8% (angiography) to 22% (caesarean delivery).

Conclusions: Through this review, we addressed a critical gap in the literature by producing the first-ever evidence-based Canadian compendium of inappropriate health care practices. Our findings can be used to advance quality improvement programs, as well as support agencies dedicated to quality and patient safety, in Canada.
Patient or healthcare consumer involvement: Several stakeholders, including patients and representatives from quality improvement organizations, across Canada were centrally involved in designing and carrying out this systematic review.