Development and validation of a Core Outcome Set for Work and other plans to improve evidence synthesis in occupational health

Article type
Authors
Hoving J1, Verbeek J2, Langendam M3, Kunz R4, Verstappen S5, Madan I6, Hulshof C2
1Amsterdam University Medical Center, Amsterdam, Netherlands; Cochrane Work & Health & Social Security
2Amsterdam University Medical Center, University of Amsterdam, Department of Public and Occupational Health, Cochrane Work, Amsterdam, Netherlands
3Amsterdam University Medical Center, University of Amsterdam, Department of Clinical Epidemiology, Biostatistics and Bioinformatics,, Amsterdam, Netherlands
4Div. Clinical Epidemiology/ Research Group Evidence Based Insurance Medicine, EbIM, Department of Clinical Research, University of Basel, Basel, Switzerland
5Centre for Epidemiology Versus Arthritis, The University of Manchester, Manchester, United Kingdom
6School of Medicine, King’s College London, London, United Kingdom
Abstract
Back ground
Over the past decades, intervention research investigating the evidence for occupational health interventions, has seen a dramatic increase in trial publications. Although the number of intervention studies and systematic reviews on topics like the prevention of sick leave and return to work is growing, advancements in the measurement of work-related outcomes in these intervention studies are lagging behind. Authors of Cochrane systematic reviews therefore consistently recommend improvements in the definition of work-related outcomes and their standardized use.

Aim of research program
Recognizing the need for international consensus on the measurement of work outcomes in intervention research, an international consortium of researchers, supported by Cochrane Work and Cochrane Insurance Medicine (united in the Cochrane Work & Health & Social Security Thematic Group: https://www.cochrane.org/about-us/our-global-community/thematic-groups/work-health-and-social-security) has launched several studies as part of the ‘Core Outcome Set-For-Work’ research program (www.cosforwork.org) which is now entering its second phase.

Results of COS methods development
The presentation will highlight several studies leading up to the development of a Core Outcome Set for Work, including practical examples that show some of the challenges for stakeholders to agree on something as vital as work outcomes. The presentation will also include the Core Outcome Set itself. Although we have defined ‘which’ outcomes COS for Work should measure, such as return to work, more research is planned to investigate ‘how’ these COS outcomes can be measured in the form of self-report and in registries. In addition, plans for further studies on COS for Work, including its implementation, are planned and will form part of the presentation.

Discussion
Other Cochrane review groups, methods groups and thematic groups could benefit from considering our COS-for-Work as work participation is often an important outcome for patients. Looking at evidence synthesis within occupational health, there is not only a need for more international consensus and harmonisation of work outcomes, but also a need adopt, refine or develop current classifications for interventions and (worker) populations in occupational health. Thoughts on how to proceed are likewise presented, including a recent initiative to collaborate on the topic of evidence synthesis in occupational health (www.evidenceforwork.org).