Article type
Abstract
"Background: Given the projected trends in population aging and population growth, the number of people with dementia is expected to increase. The previous studies suggested that population growth and ageing will lead to 2.7 times more dementia cases globally in 2050 than in 2019. The average total national expenditure on dementia estimated as a proportion of GDP in LMICs was 0.45%. Although studies on the economic burden of dementia among people has been published, there is no meta-analysis regarding the healthcare, patient/family, lost productivity, and societal costs for this condition.
Objective: This systematic review and meta-analysis is conducted to quantitatively estimate the direct cost, indirect cost, and resources among people with dementia.
Methods:
Search strategy: Four databases such as PubMed, Embase, Web of science, and China Biology Medicine were searched from inception to 28th February 2024 to identify published articles relevant to the research objectives. The search focused on three main areas: dementia, costs, and observational studies;
Risk of bias: We assessed the risk of bias of the included studies using a checklist based on the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) 2020 statement used and recommended by previous systematic reviews of cost-of illness studies;
Data extraction: We extracted the following data for each included study: author(s); year of publication; aims/purpose; study population and sample size; study design; source data; details of cost data: country, currency, reference year, perspective (health care, patient/family and societal), time horizon, cost categories; Data synthesis: We estimated the economic burden of dementia in US 2024 dollars. Using the purchasing power parities (PPP), we converted different currencies into US dollars for the relevant years. Then we inflated the costs to US dollars ($) in August 2024 using the Consumer Price Index Inflation calculator developed by the US Bureau of Labor Statistics. If studies provided a comparison group (severe dementia vs mild/very mild dementia or dementia vs non-dementia), means and SDs of each group were used to estimate the incremental costs and 95% confidence intervals (CIs).
Result and Conclusion: This study is ongoing and results will be presented at the Summit as available. "
Objective: This systematic review and meta-analysis is conducted to quantitatively estimate the direct cost, indirect cost, and resources among people with dementia.
Methods:
Search strategy: Four databases such as PubMed, Embase, Web of science, and China Biology Medicine were searched from inception to 28th February 2024 to identify published articles relevant to the research objectives. The search focused on three main areas: dementia, costs, and observational studies;
Risk of bias: We assessed the risk of bias of the included studies using a checklist based on the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) 2020 statement used and recommended by previous systematic reviews of cost-of illness studies;
Data extraction: We extracted the following data for each included study: author(s); year of publication; aims/purpose; study population and sample size; study design; source data; details of cost data: country, currency, reference year, perspective (health care, patient/family and societal), time horizon, cost categories; Data synthesis: We estimated the economic burden of dementia in US 2024 dollars. Using the purchasing power parities (PPP), we converted different currencies into US dollars for the relevant years. Then we inflated the costs to US dollars ($) in August 2024 using the Consumer Price Index Inflation calculator developed by the US Bureau of Labor Statistics. If studies provided a comparison group (severe dementia vs mild/very mild dementia or dementia vs non-dementia), means and SDs of each group were used to estimate the incremental costs and 95% confidence intervals (CIs).
Result and Conclusion: This study is ongoing and results will be presented at the Summit as available. "