Article type
Abstract
Background:
The GRADE-ADOLOPMENT methodology has been widely used to adopt, adapt, or de novo develop recommendations from existing or new guideline and evidence synthesis efforts. This guidance refines the operationalization for applying GRADE-ADOLOPMENT.
Methods:
Through iterative discussions, online meetings, and email communications, the GRADE-ADOLOPMENT Project Group drafted the updated guidance. We then conducted a review of handbooks of guideline-producing organizations and a scoping review of published and planned adolopment guideline projects. The lead authors refined the existing approach based on the scoping review findings and feedback from members of the GRADE Working Group. We then presented our approach and discussed it during the GRADE-ADOLOPMENT project group meetings held in July 2022 (20 people), September 2022 (15 people), October 2022 (17 people), November 2022 (20 people), March 2023 (23 people), and April 2023 (21 people). We presented the initial results to GRADE Working Group members for discussion and feedback in November 2022 (115 people) and in May 2023 (approximately 100 people) and twice to the GRADE Working Group in September 2023 (approximately 60 and 90 people). It was first approved at the Glasgow meeting in September 2023 by approximately 89 members of the GRADE Working Group and then by the GRADE Guidance Group on November 22, 2023.
Results:
This GRADE guidance shows how to effectively and efficiently contextualize recommendations using the GRADE-ADOLOPMENT approach by (1) showcasing alternative pathways for starting an adolopment effort; (2) elaborating on the different essential steps of this approach, such as building on existing Evidence-to-Decision (EtD) frameworks when available or developing new EtDs if necessary; and (3) providing examples from adolopment case studies to facilitate the application of the approach. We demonstrate how to use contextual evidence to make judgments about EtD criteria and highlight the importance of making the resulting EtDs available to facilitate adolopment efforts by others.
Conclusion:
This updated GRADE guidance further operationalizes the application of GRADE-ADOLOPMENT based on over 6 years of experience. It serves to support uptake and application by end users interested in contextualizing recommendations to a local setting or specific reality in a short period of time or with limited resources.
The GRADE-ADOLOPMENT methodology has been widely used to adopt, adapt, or de novo develop recommendations from existing or new guideline and evidence synthesis efforts. This guidance refines the operationalization for applying GRADE-ADOLOPMENT.
Methods:
Through iterative discussions, online meetings, and email communications, the GRADE-ADOLOPMENT Project Group drafted the updated guidance. We then conducted a review of handbooks of guideline-producing organizations and a scoping review of published and planned adolopment guideline projects. The lead authors refined the existing approach based on the scoping review findings and feedback from members of the GRADE Working Group. We then presented our approach and discussed it during the GRADE-ADOLOPMENT project group meetings held in July 2022 (20 people), September 2022 (15 people), October 2022 (17 people), November 2022 (20 people), March 2023 (23 people), and April 2023 (21 people). We presented the initial results to GRADE Working Group members for discussion and feedback in November 2022 (115 people) and in May 2023 (approximately 100 people) and twice to the GRADE Working Group in September 2023 (approximately 60 and 90 people). It was first approved at the Glasgow meeting in September 2023 by approximately 89 members of the GRADE Working Group and then by the GRADE Guidance Group on November 22, 2023.
Results:
This GRADE guidance shows how to effectively and efficiently contextualize recommendations using the GRADE-ADOLOPMENT approach by (1) showcasing alternative pathways for starting an adolopment effort; (2) elaborating on the different essential steps of this approach, such as building on existing Evidence-to-Decision (EtD) frameworks when available or developing new EtDs if necessary; and (3) providing examples from adolopment case studies to facilitate the application of the approach. We demonstrate how to use contextual evidence to make judgments about EtD criteria and highlight the importance of making the resulting EtDs available to facilitate adolopment efforts by others.
Conclusion:
This updated GRADE guidance further operationalizes the application of GRADE-ADOLOPMENT based on over 6 years of experience. It serves to support uptake and application by end users interested in contextualizing recommendations to a local setting or specific reality in a short period of time or with limited resources.