Article type
Abstract
"Background: Well-conducted and reported clinical practice guidelines of best available evidence are recognized as the best approach to inform policy and practice. Previous studies have confirmed that prospective registration of protocols for clinical trials and systematic reviews was associated with increased quality. However, there is a lack of empirical evidence about whether prospective registration improves the overall methodological and reporting quality of practice guidelines.
Objective: This study aims to explore trends in prospective registration of practice guidelines and to analyze how do basic characteristics, methodological and reporting quality differ between guidelines with and without prospective registration.
Methods: English (MEDLINE) and Chinese (CBM and Wanfang Data) databases were searched to identify guidelines published in peer-reviewed journals from 2021 to 2023. After titles, abstracts and full texts screening, potentially relevant guidelines were divided into two groups: registered guidelines and nonregistered guidelines. Registration status was decided according to whether the registration information (including registration number and/or registry name) was provided in abstract or full text. For each group, random number tables were generated, and the first 100 eligible guidelines from each group were randomly selected. Data of interest from guidelines were extracted, and the AGREE II tool and RIGHT checklist were used to appraise the methodological and reporting quality of the included guidelines, respectively.
Results: Initial literature search retrieved 16,895 citations. The identification and selection of guidelines are in progress. The detailed results will be presented at the Colloquium.
Conclusions: Quality, transparency and currency are cornerstones of guidelines. With the increasing number of guidelines globally, and awareness of prospective registration among developers, our study will provide directions for future.
Patient, public and/or healthcare consumer involvement: NA. "
Objective: This study aims to explore trends in prospective registration of practice guidelines and to analyze how do basic characteristics, methodological and reporting quality differ between guidelines with and without prospective registration.
Methods: English (MEDLINE) and Chinese (CBM and Wanfang Data) databases were searched to identify guidelines published in peer-reviewed journals from 2021 to 2023. After titles, abstracts and full texts screening, potentially relevant guidelines were divided into two groups: registered guidelines and nonregistered guidelines. Registration status was decided according to whether the registration information (including registration number and/or registry name) was provided in abstract or full text. For each group, random number tables were generated, and the first 100 eligible guidelines from each group were randomly selected. Data of interest from guidelines were extracted, and the AGREE II tool and RIGHT checklist were used to appraise the methodological and reporting quality of the included guidelines, respectively.
Results: Initial literature search retrieved 16,895 citations. The identification and selection of guidelines are in progress. The detailed results will be presented at the Colloquium.
Conclusions: Quality, transparency and currency are cornerstones of guidelines. With the increasing number of guidelines globally, and awareness of prospective registration among developers, our study will provide directions for future.
Patient, public and/or healthcare consumer involvement: NA. "