How often do guideline developing groups adopt the GRADE-ADOLOPMENT approach? A rapid review

Article type
Authors
Posadzki P1
1Kleijnen Systematic Reviews, Escrick, Yorkshire, United Kingdom
Abstract
"Background: The Grading of Recommendations Assessment, Development and Evaluation (GRADE)-ADOLOPMENT approach to guideline production combines adoption, adaptation, and, if needed, de novo development of recommendations which then inform clinical practice. GRADE Evidence to Decision (EtD) framework is the core component of the approach, as it presents best scientific evidence that is context/setting specific and transparent, further enhancing acceptability and credibility of the guidelines and recommendations.
Aim: This rapid review is aimed at estimating the prevalence of GRADE-ADOLOPMENT approach used by guideline developers worldwide.
Method: PubMed, Cochrane Central and Google Scholar were searched on 17 January 2024 (from January 2017-present) for potentially relevant papers. Only guidelines that specifically followed the GRADE-ADOLOPMENT methodology were eligible. Those guidelines or recommendations using e.g., ADAPTE process were excluded.
Results: Over the past seven years, only sixteen clinical practice guidelines (CPG) employing the GRADE-ADOLOPMENT methodology were published. Those guidelines/recommendations originated from Argentina (n=1), Czech Republic (n=3), Eastern Mediterranean Region (n=1), Italy (n=1), Mexico (n=1), Pakistan (n=4), Trinidad and Tobago (n=1), Saudi Arabia (n=2), Tunisia (n=1), UK (n=1); and pertained to the following conditions: antibiotic management (n=2), breast cancer screening (n=1), chronic kidney disease (n=1), chronic respiratory conditions (n=1), colon cancer screening (n=1), COVID-19 (n=1), diabetes mellitus (n=2), hyperthyroidism (n=1), incisional hernia (n=1), osteoporosis (n=2), physical activity (n=1), rheumatoid arthritis (n=2). All documents were published in English.
Conclusions: The adoption of GRADE-ADOLOPMENT methodology, is, still suboptimal. Significant monetary and non-monetary savings could be made by guideline developers worldwide by using the GRADE-ADOLOPMENT approach. Especially low and middle-income countries where the resources are scarce should benefit from GRADE-ADOLOPMENT. "