Article type
Abstract
Background: In recent years, the number of adolescents with depression has increased year by year, and the age is showing a trend of younger. Adolescents with depression face many challenges in emotional and behavioral responses, while the intervention measures for adolescent depression are still controversial.
Objective: The purpose of establishing the Evidence Gap Map (EGM) is to collect and visualize existing randomized controlled studies on interventions for depression in adolescents, to explore effective interventions, and to inform future studies.
Methods: We conducted a comprehensive search in multiple databases. Through screening randomized controlled trials on adolescent depression, extracting and summarizing valid data, epi-Mapper mapping tool was applied to present the identified studies.
Results: This EGM framework presented as a matrix of interventions (rows) and outcomes (columns). 234 non-pharmacological interventions (NPIs) were included in this analysis, The most commonly NPIs were cognitive behavioral therapy (106 studies, 45.3%) and others (77 studies, 33.0%). Interventions were categorized combines elements of NPIs including acceptance and commitment therapy (n=3), mindfulness (n=27), music (n=6), exercise (n=9), cognitive behavioral therapy (n=106), repetitive transcranial magnetic stimulation (n=6) and other interventions (n=77). Intervention outcomes primarily centered around changes in relief of the depressive mood (n=20) and reduction of anxiety (n=26) were the most reported outcomes in the primary studies. Most NPIs have demonstrated effective improvements in adolescent one or more health or emotional outcomes among depression.
Conclusion: These findings can help optimize interventions for depression in adolescents and provide evidence-based advice on depression for individuals seeking to improve their health and well-being.
Funding No 23JRZA375, Lzujbky-2022-56.
Objective: The purpose of establishing the Evidence Gap Map (EGM) is to collect and visualize existing randomized controlled studies on interventions for depression in adolescents, to explore effective interventions, and to inform future studies.
Methods: We conducted a comprehensive search in multiple databases. Through screening randomized controlled trials on adolescent depression, extracting and summarizing valid data, epi-Mapper mapping tool was applied to present the identified studies.
Results: This EGM framework presented as a matrix of interventions (rows) and outcomes (columns). 234 non-pharmacological interventions (NPIs) were included in this analysis, The most commonly NPIs were cognitive behavioral therapy (106 studies, 45.3%) and others (77 studies, 33.0%). Interventions were categorized combines elements of NPIs including acceptance and commitment therapy (n=3), mindfulness (n=27), music (n=6), exercise (n=9), cognitive behavioral therapy (n=106), repetitive transcranial magnetic stimulation (n=6) and other interventions (n=77). Intervention outcomes primarily centered around changes in relief of the depressive mood (n=20) and reduction of anxiety (n=26) were the most reported outcomes in the primary studies. Most NPIs have demonstrated effective improvements in adolescent one or more health or emotional outcomes among depression.
Conclusion: These findings can help optimize interventions for depression in adolescents and provide evidence-based advice on depression for individuals seeking to improve their health and well-being.
Funding No 23JRZA375, Lzujbky-2022-56.