A meta-analysis into the mediatory effects of family planning utilization on complications of pregnancy in women of reproductive age

Article type
Authors
Jahanfar S1, Jahanfar S2, Maurer O1, Rajkumari A1, Steinfeldt M1, Ali M1, Duque T1, Hanumantha setty S
1Tufts School of Medicine, Boston, MA, United States
2World Health Organization , Geneva, Geneva, Switzerland
Abstract
Background: Studies on statistics indicate a possible reduction in unfavorable effects through family planning in light of contradictory findings in the present body of research addressing the correlation between the use of contraceptives and maternal health outcomes. For this reason, conducting a thorough assessment of family planning's ability to reduce maternal health problems is essential.
Objectives: This systematic study aims to investigate how using contemporary contraceptives affects mother's health.
Search Methods: This study has been registered on Prospero (CRD42022332783), utilizing a comprehensive search across many databases with no geographical limitations and a deadline of February 2022.
Selection Criteria: The review includes non-RCTs with a comparison group and observational studies, such as cross-sectional, cohort, and case-control studies. Reviews that are not included in the analysis include systematic reviews, scoping reviews, narrative reviews, and meta-analyses.
Main Results: The evaluation included nineteen research, of which five showed a correlation between improved access to family planning services and the use of contraceptives and a decrease in maternal mortality. Furthermore, three studies examined the effect of contraception on the risk of preeclampsia, and the results showed that users of contraception had a reduced risk of preeclampsia (about 6%; 95% CI 0.82-1.13) than non-users. The impact of hormonal contraceptives on postpartum glucose tolerance was the subject of two studies; low-androgen contraception was associated with a lower risk of gestational diabetes (OR 0.84, 95% CI 0.58-1.22), while DMPA injection may have a higher risk of postpartum glucose status decline (OR 1.42, 95% CI 0.85-2.36). When high-risk pregnancies and deliveries were evaluated, those who used contraception in any way had a 30% decreased risk (95% CI 0.61, 0.80), albeit statistical significance was only seen in the latter scenario. Further investigation revealed that several contraceptives were linked to unfavorable results for the health of the mother, such as ectopic pregnancy and pregnancy-related venous thromboembolism.