Objectives:

This session delves into the processes and impacts of developing national guidelines and evidence syntheses at the Czech National Institute for Quality and Excellence in Health (NIKEZ). It aims to:

*Detail the methodology employed by NIKEZ in the development of national health guidelines, rapid recommendations, and evidence syntheses, emphasizing rigor, transparency, and stakeholder engagement.

*Showcase the implementation and outcomes of these guidelines within the Czech health care system, highlighting improvements in health care quality, patient safety, and policy coherence.

*Address the challenges encountered in the synthesis of evidence and the formulation of guidelines, including evidence gaps, stakeholder alignment, and the translation of guidelines into practice.

*Foster a discussion on future directions for evidence synthesis and guideline development, considering technological advancements and international collaboration.

Description of Activities and Interaction Plans:
Featuring a series of expert-led presentations, interactive panel discussions, and case study analyses, this session offers a comprehensive exploration of NIKEZ's approach to guideline development and evidence synthesis.

Activities include:

Presentations by NIKEZ Experts: An overview of the methodologies for evidence gathering, analysis, and guideline development, supplemented by real-world examples of guidelines that have significantly impacted health care delivery in the Czech Republic.
Case Study Analyses: Detailed discussions on specific instances of guideline implementation, focusing on the process from development to practice, and the resultant health care improvements.
Interactive Panel Discussions: Panels comprising international guideline developers, health care practitioners, and policymakers, aimed at exchanging experiences, challenges, and solutions in guideline development and implementation.

Target Audience:

This session is designed for a broad audience, including health care policymakers, guideline developers, clinicians, researchers, and patient advocacy groups, who are interested in the intricacies of evidence synthesis and national guideline development.

Level of Knowledge:
Although the session is structured to be accessible to participants with a general understanding of evidence-based health care practices, it also offers in-depth insights into guideline development processes, making it suitable for attendees with advanced knowledge in the field. Participants will benefit from a foundational understanding of evidence-based medicine and guideline development processes.