Article type
Abstract
"Background: People with multiple sclerosis (PwMS) report benefits from occupational therapy (OT). With the last Cochrane systematic review conducted two decades ago, there is a critical need for updated evidence.
Aims: This Cochrane review aims to synthesize the benefits and harms of OT interventions on daily functioning, participation, and quality of life in PwMS. It also explores variations based on intervention format (individual or group) and service delivery location (outpatient, inpatient, or home-based therapy).
Methods: Standard Cochrane (OF rigorous) systematic review methods were used. Two authors independently conducted systematic searches across databases (CENTRAL, MEDLINE, Embase, CINAHL, PsycINFO, Web of Science) for controlled clinical trials of OT in PwMS. Primary outcome measures (daily functioning, quality of life, participation and adverse effects) were assessed, and risk of bias and overall quality were evaluated using Cochrane RoB2/ROBINS-I and GRADEproGDT.
Results: The electronic search yielded 12,570 articles (7,388 after de-duplication). Based on title and abstract 7,170 items were excluded, remaining 218 articles for full-text screening. Results, expected by May 2024, will be presented, encompassing a summary of findings table, potential meta-analysis results in a forest plot, and insights into health equity considerations.
Discussion: The review findings are expected to benefit people with MS by influencing the evidence-based decisions of occupational therapists, policymakers, and healthcare organizations. They will inform guideline development, and aid researchers by pinpointing knowledge gaps.
Funding: Elizabeth Casson Trust, UK; Evidence Synthesis Ireland, Ireland
"
Aims: This Cochrane review aims to synthesize the benefits and harms of OT interventions on daily functioning, participation, and quality of life in PwMS. It also explores variations based on intervention format (individual or group) and service delivery location (outpatient, inpatient, or home-based therapy).
Methods: Standard Cochrane (OF rigorous) systematic review methods were used. Two authors independently conducted systematic searches across databases (CENTRAL, MEDLINE, Embase, CINAHL, PsycINFO, Web of Science) for controlled clinical trials of OT in PwMS. Primary outcome measures (daily functioning, quality of life, participation and adverse effects) were assessed, and risk of bias and overall quality were evaluated using Cochrane RoB2/ROBINS-I and GRADEproGDT.
Results: The electronic search yielded 12,570 articles (7,388 after de-duplication). Based on title and abstract 7,170 items were excluded, remaining 218 articles for full-text screening. Results, expected by May 2024, will be presented, encompassing a summary of findings table, potential meta-analysis results in a forest plot, and insights into health equity considerations.
Discussion: The review findings are expected to benefit people with MS by influencing the evidence-based decisions of occupational therapists, policymakers, and healthcare organizations. They will inform guideline development, and aid researchers by pinpointing knowledge gaps.
Funding: Elizabeth Casson Trust, UK; Evidence Synthesis Ireland, Ireland
"