Summary of best evidence for self-management of patients with receiving oral warfarin therapy

Article type
Authors
Hu R1, Duan S1, Zhu X1, Ou Q1, Wu L1
1Xiamen Cardiovascular Hosptital,Xiamen University, Xiamen, Fujian Province, China
Abstract
Background
Given the limitations of traditional anti-coagulation management and monitoring, the effectiveness of self-management in oral warfarin patients has been established. Therefore, there is an urgent need to integrate standardized practice strategies to promote its implementation among the patient population.
Objectives
This study aims to search and summarize the evidence supporting self-management practices in patients taking warfarin.
Methods Two researchers independently conducted comprehensive searches across multiple databases, including Up To Date, Guidelines International Network(GIN), National Guideline Clearinghouse(NGC), National Institute for Health and Care Excellence(NICE), Registered Nurses' Association of Ontario(RNAO), Joanna Briggs Institute Evidence-Based Practice Database(JBI), Cochrane Library, PubMed, Web of Science, Embase,Cumulative Index to Nursing and Allied Health Literature (CINAHL), China National Knowledge Infrastructure (CNKI), Wanfang Data,and other professional websites. The types of evidence encompassed clinical decisions,guidelines,evidence summaries,Systematic reviews,and expert consensus. The search period extended until June 2023.The AGREE II tool was utilized to assess the quality of the guidelines, while the JBI 2016 quality evaluation tool was employed to evaluate the systematic review. Additionally, a method for evaluating the quality of original literature types was applied to assess evidence summaries and clinical decisions.This study protocol has been registered on Fudan University's Evidence-Based Nursing Center's Evidence Summary registration platform with registration number ES20233384.
Results
A total of six literature sources were included in this review comprising one clinical decision,two guidelines,two systematic reviews and one evidence summary. From these sources,a total of 17 pieces of evidence were extracted covering four key aspects:assessment, health education, self-testing, dose adjustment, and follow-up.
Conclusions
The present study provides a comprehensive synthesis of the most robust evidence on self-management strategies for patients receiving oral warfarin therapy. This valuable information can serve as a reference for assessing and training patients in self-management, monitoring anti-coagulation levels, and implementing effective follow-up management protocols. Ultimately, these findings aim to enhance the safety of anti-coagulation therapy and improve patient satisfaction with their medical treatment.