Background: SEA-ORCHID (South East Asia -Optimising Reproductive and Child Health in Developing Countries) is a five-year project that aims to improve the health of mothers and babies across nine centres in four South East Asian countries by increasing the capacity for generating and implementing evidence. Objective: To describe the impact of the SEA-ORCHID Project on usage of The Cochrane Library at the two participating Malaysian sites and on the overall Malaysian contribution to the Library. Methods: A survey of clinicians and nurses at the two participating sites was conducted pre-intervention in 2005 and again in 2008 following a two-year educational intervention intended to increase the uptake of evidence and encourage participation in Cochrane reviews. Four Cochrane review workshops were held as part of the intervention. Data on the contribution of Malaysians to The Cochrane Library were collected pre-and post-intervention. Results: A total of 278 and 666 clinical staff were surveyed pre-and post-intervention respectively. Staff who had heard of the Library increased from 41% to 77%. Of these, over three-quarters used the Library more than once a month post-intervention compared to a third pre-intervention. Those who found the Library helpful or sometimes helpful increased from 46% to 84%. A separate survey of final year medical students showed awareness of the Library increased from 22% to 90%. In 2004, there were five reviews with Malaysian authors. By April 2009 this had increased to 19 reviews, 17 protocols and three registered titles. Over the same time, the number of Malaysian authors increased from nine to 58. During the intervention period, full-text views of The Cochrane Library more than doubled across Malaysia. Conclusion: There has been a considerable increase in Cochrane activity in Malaysia, both in terms of usage of the Library and in the production of Cochrane reviews. Funding Statement: SEA-ORCHID is jointly funded by the National Health and Medical Research Council of Australia (No. 307703) and Wellcome Trust, United Kingdom (071672/Z/03/Z).