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Poster A bibliometric analysis of the 100 most cited Cochrane reviews
2009 Singapore
Uthman, Okwundu
Background: Systematic reviews can be very useful decision making tools because they objectively summarize large amounts of information, identify gaps in medical research and identify beneficial or harmful interventions. The number of citations an article receives after its publication reflects its…
Poster A call to heighten quality of education in developing systematic reviews concerning traditional Chinese medicines in China
2009 Singapore
Yang, Zhuo, Zeng, Wu
Background: The Chinese Cochrane Centre has conducted education and training for Cochrane systematic reviews since it was officially endorsed by the Chinese Ministry of Health in July 1997. Hitherto, nearly 1700 Chinese authors from all over China have attended training events and more than 500…
Poster A comparison of handsearching versus Chinese BioMedical (CBM) database searching to identify reports of randomized controlled trials
2009 Singapore
Zhang, Ai, Duan, Wiffen
Background: The Cochrane highly sensitive search strategy (HSSS) can identify about 80% of randomized controlled trials (RCTs) in MEDLINE. No related research exists on how to identify RCTs in Chinese databases. Objective: To compare handsearching to a CBM search to identify RCTs by using the…
Oral A critique and guide of methods to assess interactions in individual patient data (IPD) meta-analysis
2009 Singapore
Fisher, Copas, Tierney, Parmar
Background and Objectives: Treatments may be more effective in some patients than others, and IPD meta-analysis provides perhaps the best method of investigating treatment-covariate interactions. We aimed to review the various methods currently used in practice, and provide a comprehensive critique…
Poster A descriptive analysis of pediatric trials published in 2007
2009 Singapore
Hamm, Hartling, Milne, Tjosvold, Curtis, Vandermeer
Background: Randomized controlled trials (RCTs) are important in informing high quality clinical care. Information is needed to improve the design, conduct and reporting of these studies for child health. Objectives: To describe a representative sample of paediatric RCTs published in 2007, with a…
Poster A good method to promote evidence-based medicine into clinical practice in Taiwan? A clinical pharmacist’s perception
2009 Singapore
Chin Lin, Bin Huang, Lien Hung, Lai Tseng
Background: Evidence-based patient care has become an important issue in recent years. Many efforts have been tried to introduce evidence-based medicine (EBM) to all clinicians and medical workers, such as nurses, pharmacists or technicians, to improve the quality of patient care. Various types of…
Oral A new format for Plain Language Summaries: does it improve understanding, and is it useful and preferable?
2009 Singapore
Santesso, Glenton, Ciapponi, Stromme Nilsen, Pardo Pardo, Rader
Background: Many research organisations now have a mandate to translate their research evidence to patients and the public. How to successfully translate it, has not yet been determined. Plain Language Summaries (PLS) of Cochrane reviews aim to summarise the research evidence from systematic…
Oral A randomized controlled trial evaluating the effectiveness of three knowledge translation and exchange interventions among public health decision makers
2009 Singapore
Dobbins, DeCorby, Robeson
Background: Public health (PH) decision makers require a coordinated multi-component approach to support evidence-informed decision making (EIDM). Objectives: To evaluate the effectiveness of three knowledge translation and exchange (KTE) strategies in promoting the use, in PH decision making, of…
Poster A simulation study of methods for imputing data from continuous outcomes: effects on results from primary studies and results from meta-analysis
2009 Singapore
Odgaard-Jensen
Background: Loss to follow-up or drop-out is often a major concern when analysing data from primary studies, but also when extracting data from these for use in systematic reviews. The policy of the Cochrane Collaboration is that data used in a Cochrane review should, if possible, be based on the…
Poster A survey analysis of doctors’ and patients’ perceptions of shared decision making in China
2009 Singapore
Zhang, Wang, Dong, Chen, Wang, Fan, Zhou, Liu, Wan, Zhang
Background: The concept of shared decision making has received increasing interest in recent years. But both patients and doctors still have difficulties in shared decision making in China. Objectives: To investigate the attitudes of both doctors and patients towards shared decision making and to…
Poster A systematic review of N-of-1 methods, analysis and meta-analysis
2009 Singapore
Vohra, Shamseer, Bukuta, Sampson, Barrowman, Moher
Background: An N-of-1 trial is a randomized, multiple cross-over evaluation performed in a single subject. While many N-of-1 designs and statistical methods have been reported, the most efficient and rigorous methods for conducting and analyzing N-of-1 trial results have yet to be identified.…
Poster A unique approach to extend the reach of Cochrane reviews to public health practitioners: the Cancer Control
2009 Singapore
Prabhu Das, Vinson
Background: The systematic evidence review synthesizes the scope of relevant research to inform public health practitioners about what works, what does not, and where evidence is insufficient. Cancer control practitioners require access to evidence reviews for implementing evidence-based public…
Poster Access to evidence from countries in South Asia: the South Asian Database of Controlled Clinical Trials and the South Asian Cochrane Network and Centre’s Digital Library
2009 Singapore
Barnabas, Yamuna, Parthasarathy, Venkatesh, Tharyan
Background: Many trials conducted in middle and low income countries are published in journals that are not indexed in commonly searched databases. Their exclusion from systematic reviews could bias conclusions, rendering them unreliable and potentially irrelevant to healthcare in these countries.…
Poster Adaptation as method for clinical practice guideline development or implementation: a systematic review update
2009 Singapore
Sebastian Castillo, Andrea Mosquera, Marcela Torres, Reveiz, Rocio Tellez, Antonio Buendia, Pardo
Background: Clinical practice guideline (CPG) development is a useful strategy for healthcare quality improvement, although is logistically and financially demanding. There are important differences in resources between developed and developing countries. Some researchers have advocated the use of…
Poster Additional literature search in Cochrane reviews: how, what and why?
2009 Singapore
J Mathew, L Mathew
Background: Explicit and exhaustive literature search are hallmarks of Cochrane reviews; therefore authors commit to perform additional searches in and through conference proceedings, handsearching non-indexed journals, etc. However, the process, outcomes and therefore benefit (or otherwise) of…
Oral An empirical assessment of the validity of uncontrolled comparisons of the accuracy of diagnostic tests
2009 Singapore
Takwoingi, Dinnes, Leeflang, Deeks
Background: Cochrane reviews of diagnostic test accuracy aim to provide evidence to support the selection of diagnostic tests by comparing the performance of tests or test combinations. Studies that directly compare tests within patients or between randomized groups are preferable but are uncommon…
Oral An equity lens for identifying priority topics for Cochrane reviews
2009 Singapore
Nasser, Welch, Tugwell, Ueffing, Bastian
Background: Different methods have been suggested for setting priorities for research. Priority setting for health research should include the views and needs of different stakeholders and ideally considers the impact of healthcare interventions on different socioeconomic groups and the…
Oral An exploratory analysis of lumping and splitting in systematic reviews
2009 Singapore
Weir, Mayhew, Fergusson, Grimshaw
Background: A key issue for systematic reviewers is how broad or narrow their research question should be in terms of populations, interventions, study designs and outcomes. The scope may have implications on the findings and generalizeability of the review. Health professional behaviour change…
Poster Analytic methods to bridging the gap between randomized controlled trials and observational studies
2009 Singapore
Kitio Dschassi, Cecchin, Dosquet
Background: Causal inferences can be drawn from both randomized experiments and observational studies. Unlike randomized controlled trials, where randomization theoretically balances confounding factors, observational studies pose the challenge of how to adjust appropriately for confounding. The…
Oral Applying the risk of bias tool in a systematic review of combination long-acting beta-agonists and inhaled corticosteroids for maintenance therapy of persistent asthma
2009 Singapore
Hartling, Bond, Vandermeer, Seida, Dryden, Rowe
Background: The risk of bias (ROB) tool was recently introduced by the Cochrane Collaboration to assess internal validity of randomized trials. Objectives: To evaluate (1) inter-rater agreement of the ROB tool, (2) time to access supplemental study information, (3) concurrent validity compared to…