Background: Tackling global health inequalities requires systematic reviews of relevance to low and middle income countries (LMICs). Strategies are needed to identify and include research literature conducted in LMICs, much of which is not indexed by major international research databases. The Cochrane Opportunities Fund funded four Cochrane entities to develop an approach for locating this research with a particular focus on countries that have been otherwise under-engaged or under-addressed across the Collaboration. Objectives: To identify a key set of databases and other sources containing intervention studies from LMICs. To evaluate and describe these in relation to a number of factors including: topic coverage, ease of searching, and implications for translation. To identify and support volunteers to handsearch journals and other information sources. To develop appropriate systems to support submission of studies by volunteers which are compatible with range of review and reference management systems. Methods: LMIC databases and other sources were identified by a collaboration of Cochrane entities, an international group of researchers and information experts. Databases and sources were evaluated and described. EPPI-Reference, a web-based register and submission system, was developed which incorporates a simple text form, for volunteers without regular internet access, and is compatible with other reference management software. Results: To date over 60 databases and other sources have been identified, evaluated and described. These range from resources with extensive global coverage to those dedicated to 23 individual countries including Iran, Hungary, Thailand, South Africa, Pakistan and India. The current list is available at http://epocoslo.cochrane.org/en/newPage2.html. Volunteer handsearchers have been contacted and support systems put in place. Barriers and enablers to involvement have been noted and will be described. Conclusions: Systems to improve access to hard to identify LMIC research can be developed, and be enhanced by further field trials and support.