Background: Health Policy and Systems Research (HPSR) can be defined as the production of new knowledge to improve how societies organize themselves to achieve health goals. Systematic reviewers in this area face a lot of challenges in the process of identifying all the relevant literature. The wider scope of the topic and the inclusion of study designs different from RCTs make the evidence difficult to retrieve. The Program in Policy Decision-Making / Canadian Cochrane Network and Centre (PPD/CCNC) has created a database of systematic reviews (SRs) for management and policy making, which is the biggest initiative of this type to our knowledge. Objective: To describe electronic resources utilized in Cochrane SRs relevant to HPSR. Methods: We evaluated all Cochrane SRs incorporated in the PPD/CCNC database. We collected data on which electronic resources were searched. Results: We identified 198 Cochrane systematic reviews in HPSR using a total of 144 different electronic resources (excluding Cochrane groups’ registers); 54 health databases, 20 in HPSR related areas (e.g. social science, health economics), 23 databases unrelated to health, 17 sites to identify grey literature, 24 ongoing trials registers and six databases that do not contain primary studies (e.g. DARE). Each review searched in an average of 7.7 resources. MEDLINE (85%), Cochrane Group registers (80%), EMBASE (75%), CENTRAL (74%) and CINAHL (58%) were the most commonly used. 175 resources (88%) were utilized in fewer than 5% of the SRs. Conclusions: The wide variety of existing health and non-health electronic resources, make it difficult for review authors to conduct comprehensive searches. More research is urgently needed in order to establish the contribution of each of these resources. Initiatives to create a database of primary studies in HPSR of similar proportions to CENTRAL must be stimulated.