Integrating sex and gender analysis into systematic reviews of drug treatments

Article type
Year
Authors
Mintzes B1, Welch V2, Puil L3, Tudiver S4, Doull M5, Boscoe M6, Runnels V7, Shea B7, Petkovic J7
1Faculty of Pharmacy and Charles Perkins Centre, University of Sydney, Cochrane Hypertension Review Group
2Campbell and Cochrane equity methods, Cochrane Ageing
3Cochrane Hypertension, University of British Columbia, Canada
4Independent Researcher, Canada
5University of British Columbia, Canada
6Reach Community Health Centre, Vancouver, Canada
7University of Ottawa, Canada
Abstract
Objectives:
1. To understand the relevance of sex and gender analysis (SGA) to systematic reviews of healthcare interventions, using drug treatments as an example.
2. To become familiar with recently developed tools and methods for the conduct, appraisal and reporting of SGA in systematic reviews of healthcare interventions.

Description: SGA is a framework to guide systematic review authors, consumers and editors in determining the applicability of health evidence to diverse populations. There is growing consensus that SGA in systematic reviews and primary research is essential for informed decision-making, reduction of harm and promotion of health equity. We will introduce basic theoretical considerations of sex and gender and the intersection of SGA with health equity through an interactive process. A discussion will follow on the influences of sex and/or gender on various aspects of drug treatment, including decisions to treat, potential benefits, and vulnerability to harm. Small group break-out sessions will be based around the application of newly-developed tools for the conduct, appraisal, and reporting of SGA in systematic reviews to illustrative case studies of drug treatments. The small groups will report back on their experiences to the wider group of participants. The session will conclude with a discussion on some of the methodological challenges in conducting SGA, and ways to improve SGA guidance and methods.