How does the current Burden of Disease ranking (from the GBD project) compare to that of topics in Cochrane and Prospero’s SRs registered in the last 5 years by region?

Article type
Authors
Bardach A1, Glujovsky D1, Ciapponi A1
1Instituto de Efectividad Clínica y Sanitaria
Abstract
Background: Only a fraction of the world’s resources for health research and development (R&D) are spent on high burden health problems, which represent almost all of the world’s preventable mortality. This landscape study will explore the degree of correlation between burden of disease in different parts of the world with the distribution of topics addressed in Systematic Reviews registered in the two main databases. We hypothesize that SRs may capture only a small proportion of all incident evidence synthesis research, and even this could vary substantially by region.

Objectives: We aim to compare the ranking and frequency of conditions that produce a greater burden of disease according to IHME's GBD with the ranking of topics of Systematic Reviews in Cochrane and PROSPERO databases, in the last five years. Also we will explore sources of funding and the evolution of trends.

Methods: We will manually review the rankings of different health causes, diseases or risk factors, and the primary funding source by examining the registered record Cochrane, PROSPERO, and will compare it to the ranking of burden of disease in terms of DALYs and deaths, from the IHME’s GBD project according to ICD-10 codes, in all WHO world regions.

Results: We are still working on this study. Results will be shown at the Colloquium.

Conclusions: will be shown at the Colloquium.


Patient or healthcare consumer involvement: patients will have a benefit if current research reflects priorities given by the most burden diseases, especially those patients that are more vulnerable.