Methods for the evaluation of the implementation of a rapid-recommendation on COVID-19 treatment

Article type
Authors
Peuchot V1, Boietti B2, Franco J3, Escobar Liquitay C4, Sanchez Thomas D2, Torres Gomez F2, Peroni L2, Baez G5, Pisula P5, Pollan J2
1Servicio de Clínica Médica, Hospital Italiano de Buenos Aires
2Servicio de Clínica Médica, Hospital Italiano de Buenos Aires
3Departamento de Investigación, Instituto Universitario Hospital Italiano Servicio de Medicina Familiar y Comunitaria - Hospital Italiano de Buenos Aires
4 Biblioteca Central, Instituto Universitario Hospital Italiano
5Alumno, Instituto Universitario Hospital Italiano
Abstract
Background: The arrival of the COVID-19 pandemic to Argentina introduced uncertainties regarding treatment options. Initial recommendations were based on supportive care, and the use of drugs capable of inhibiting viral replication such as hydroxychloroquine or lopinavir/ritonavir was suggested by other countries that faced the first cases in the pandemic. We developed rapid recommendations for the treatment of COVID-19 following the GRADE framework.

Objectives: To evaluate compliance rates to quality of care indicators along with implementation of locally developed recommendations for the treatment of COVID-19.

Methods:We created a prospective registry of all COVID-19 cases admitted to our institution, including data of the critical outcomes that were considered when drafting these recommendations and indicators of the adequateness of the implementation of said recommendations. Considering that they were “weak” recommendations, we anticipate substantial variability. The indicators alongside the outcomes will feed to a dashboard that will be presented to the decision panel of the recommendation and the Crisis Committee of our institution in the following weeks. In addition, there will be a brief survey of the intended medical users of the recommendations to assess their views on their applicability, including barriers and enablers.

Results:We have drafted and pilot-tested the data collection forms and database. We expect to analyse the opportunities and challenges when implementing rapid recommendations in the context of a pandemic disease. We will present the results at the Colloquium

Consumer involvement:We conducted an open online poll to people in the community and healthcare professionals (>400 responses) to identify critical outcomes for SoF tables. A patient advocate was incorporated into the decision panel.