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Displaying 21 - 40 of 237 records Index
Oral Adaptation of the European Guidelines on Breast Cancer Screening to the Tunisian setting using the GRADE-ADOLOPMENT approach
2019 Santiago
Kahale, Ouertatani, Ben Brahem, Ben Hamouda, Sar Parkinsion, Akl
Background: guidelines are the cornerstone of high-quality evidence-based practice. Guidelines could be
1) developed from scratch, (i.e. de novo);
2) adopted from one setting to another as is; or
3) adapted from one setting to another taking into consideration contextual factors.
The…
Oral Agreement in the assessment of systematic reviews with the AMSTAR 2 tool: novice versus expert methodologists
2019 Santiago
Martinez-Zapata, Niño de Guzman, Canelo, Vasquez-Mejia , Merchan-Galvis , Madera-Anaya , Viteri-Garcia , Muñoz, Zaror
Background: one of the tools to assess the quality of conducting systematic reviews is the AMSTAR2 (A MeaSurement Tool to Assess systematic Reviews). We studied the agreement of AMSTAR2 between novice and expert methodologists assessing the quality of systematic reviews (SRs) addressing the…
Oral An alternative method for presenting assessments of risk of bias in systematic reviews of diagnostic test accuracy studies
2019 Santiago
Vali, Lee, Zafarmand , Bossuyt
Background: systematic reviews include primary studies that differ in sample sizes, with larger studies contributing more to the meta-analysis. At present, study size is not considered in 'Risk of bias' evaluations.
Objectives: to develop an alternative way to present the contribution…
Oral An efficient approach to identify eligible studies for 102 PICO (population, intervention, control, outcome) questions
2019 Santiago
Yaacoub, Khamis, Kahale, Durán, Rodríguez, Turner, Rada, Akl
Background: developing trustworthy practice guidelines requires the use of systematic approaches to identify relevant evidence. Some guideline projects address a large number of PICO (population, intervention, comparison, outcome) questions. This requires the use of efficient approaches for…
Oral An overview of systematic reviews on mental healthcare for refugees and asylum seekers
2019 Santiago
Uphoff, Purgato, Barbui, Churchill
Background: the Cochrane Global Mental Health network aims to support the production, dissemination, and implementation of systematic reviews relevant to mental health in low- and middle-income countries. As part of this work, we are synthesizing evidence from reviews on the effectiveness of mental…
Oral Answering the call: responsive evidence generation for guideline developers
2019 Santiago
Hine, Murray, Johnson, Walshe, Wilson, Jullien, Garner
Background: Cochrane promotes evidence-based decision making, and as such aims to support guideline development internationally. Cochrane Infectious Diseases Group (CIDG) aims to impact policy in tropical diseases in a diverse range of resource-limited settings. Our funding is contingent on…
Oral Applying the Evidence Ecosystem concept as a tool to demonstrate the successful implementation of evidence-based practice in international aid: the example of ‘Water, Sanitation and Hygiene’ (WASH)
2019 Santiago
Van Remoortel, De Buck, Schelstraete, Lievens, Vandekerckhove
Background: the Belgian Red Cross (BRC) is an aid organization with a wide range of activities, from blood collection and banking, to first-aid education, to international disaster and development aid. Evidence-based decision-making is embedded in the long-term strategic vision of BRC for all its…
Oral Are conference abstracts of systematic reviews reliable and well-reported? A case study of five consecutive World Congresses of Pain
2019 Santiago
Saric, Dosenovic, Saldanha, Jelicic Kadic, Puljak
Background: results of systematic reviews (SRs) are often presented at conferences. Examinations of conference abstracts of primary studies have repeatedly shown that information presented in abstracts is often not well reported and/or not dependable. These issues have not been examined as much in…
Oral Assessing how information is packaged in rapid reviews for policymakers and other stakeholders: a cross-sectional study
2019 Santiago
Garritty, Hersi, Hamel, Butler, Monfaredi, Nussbaumer-Streit, Cheng, Stevens, Moher
Background: rapid reviews (RRs) have become attractive products to healthcare decision makers, but what is unclear is how well they are packaged for end users so that the evidence is more readily consumed and applied. Therefore, it is important to assess how well RRs convey information in a format…
Oral Assessing the methodological quality of systematic review: the AMSTAR II-DTA extension
2019 Santiago
Cinquini, Moschetti, Minozzi
Background: in 2017, the AMSTAR II checklist was proposed as an improvement of the previous AMSTAR to assess the methodological quality of systematic reviews (SR) that include randomized or non-randomized studies of healthcare interventions. As for SRs of interventions, SRs of diagnostic accuracy (…
Oral Attitude, expectation and needs of Cochrane knowledge translation volunteers in China
2019 Santiago
Lu, Li, Liu, Qiao, Liu, Li
Background: our centre is responsible for Cochrane knowledge translation (KT) in simplified Chinese. We have run regular workshops to recruit potential volunteers since 2015. Volunteers who understand are essential for maintaining and developing the translation activities.
Objectives: to learn…
Oral Attrition bias, the use of intention-to-treat and magnitude of treatment effects in randomized controlled trials: a meta-epidemiological study
2019 Santiago
Armijo-Olivo, Da Costa, Arienti, Negrini
Background: intention-to-treat (ITT) is a gold standard strategy used to analyze the results of randomized controlled trials (RCTs). ITT analysis has been considered a indicator of methodological quality, since has been used to determine trials' quality. The extent to which the use of ITT or…
Oral Authorship diversity among systematic reviews in eyes and vision
2019 Santiago
Qureshi, Han, Fapohunda, Abariga, Wilson, Li
Background: Cochrane strives for diversity in its membership and among its authors and contributors. The inclusion of people from different backgrounds and with different lived experiences is critical to ensuring the questions addressed in systematic reviews (SRs), and the subsequent conclusions…
Oral Automated extraction of adverse drug reactions from biomedical literature and Food and Drug Administration (FDA) drug labels using machine learning
2019 Santiago
NANDAL, Piette
Background: Elsevier is a global information analytics company leveraging its rich tradition of curating and publishing leading scientific content to power clinical and research solutions. By combining content with cutting-edge technology in artificial intelligence (AI), machine learning (ML) and…
Oral Automatic generation of comprehensive trial registers for specific health conditions
2019 Santiago
Marshall, Noel-Storr, Wallace, Thomas
Background: a key problem in understanding health research is the lack of trial registers on important clinical conditions, and the difficulty keeping them updated. Here, we develop and evaluate methods for automating the process of producing topic-specific clinical trial registries.
Objectives…
Oral Automatic search strategy reformulation interface for systematic reviews
2019 Santiago
Scells, Zuccon, Koopman, Clark
Background: within the last decade the rise of digital publishing has become widespread, enabling publications to be edited and updated after the fact. In the medical domain, systematic reviews are one type of digital document that is often updated after initial publication. This is usually because…
Oral Building evidence-based public health capacity in Africa: developing and piloting a workshop
2019 Santiago
Rohwer, Burns, Akiteng, Ntawuyirushintege, Tumusiime, Namatovu, Kobusingye
Background: there is a lack of evidence-based public health (EBPH) training initiatives in Africa. The Collaboration for Evidence-based Health Care and Public Health in Africa (CEBHA+) is a network of seven African partners in Uganda, Ethiopia, Rwanda, Malawi and South Africa, and two German…
Oral Building more robust search strategies in Cochrane systematic reviews: towards improving inter-information specialists’ agreement
2019 Santiago
POSADZKI
Background: in Cochrane systematic reviews (CSRs), two review authors carry out screening and data extraction to improve accuracy and minimize any potential biases. However, typically only one librarian/information specialist is involved in building a search strategy. This might lead to bias,…
Oral Calculation of absolute risk for important outcomes in patients with and without a prognostic factor of interest
2019 Santiago
Foroutan, Iorio, Thabane, Guyatt
Background: primary studies and systematic reviews of prognosis commonly report relative measures of association between prognostic factors and outcomes of interest. For decision making, however, evidence users need the absolute risk of the outcomes in those with and without the prognostic factors…
Oral Causal chain analysis as a way of understanding how interventions work
2019 Santiago
Kneale, Thomas, Bangpan, Waddington, Gough
Background: understanding the extent to which an intervention ‘works’ can provide compelling evidence to decision-makers, although without an accompanying explanation of how an intervention works, this evidence can be difficult to apply in other settings, which ultimately impedes its usefulness in…